Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11038924 | 0.88 | ADORA3 (0.47) | ADORA3ADORA1TP53 | |
| SCHEMBL11037267 | 0.71 | GRIN2D (0.48) | ADORA3 | |
| SCHEMBL11037216 | 0.69 | GRIN2D (0.41) | — | |
| SCHEMBL31093975 | 0.69 | GABRA5 (0.55) | ADORA3ADORA1 | |
| SCHEMBL1278798 | 0.69 | GABRA5 (0.55) | ADORA3ADORA1 | |
| SCHEMBL11066435 | 0.68 | GRIN2D (0.40) | — | |
| SCHEMBL10747539 | 0.68 | ADORA3 (0.50) | ADORA3ADORA1 | |
| SCHEMBL10846576 | 0.68 | HTR2C (0.61) | HTR2C | |
| SCHEMBL10844640 | 0.68 | HTR2C (0.66) | HTR2CTP53 | |
| SCHEMBL7340895 | 0.68 | HTR2C (0.66) | HTR2CTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0040401-B1 | TRIAZOLOQUINOXALIN-4-ONES AND SUCH OXALINE-4-THIONES | USV PHARMACEUTICAL CORPORATION (US) | 1984-03-21 | — | — | EP | disclosed |
| US-4354027-A | HYPOTENSIVE AGENTS | USV PHARMACEUTICAL CORPORATION (US) | 1982-10-12 | — | — | US | disclosed |
| EP-0040401-A1 | Triazoloquinoxalin-4-ones and such oxaline-4-thiones | USV PHARMACEUTICAL CORPORATION (US) | 1981-11-25 | — | — | EP | disclosed |