Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.77 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.77 |
| ▸ | HTT | P42858 | 2/20 | 0.77 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5483513 | 0.87 | HSD17B10 (0.72) | HSD17B10ADORA2AHTTADRA2AKDM4E | |
| SCHEMBL11008493 | 0.81 | HTT (0.59) | HSD17B10ADORA2AHTTADRA2AKDM4E | |
| SCHEMBL7011406 | 0.79 | ADORA2A (0.70) | HSD17B10ADORA2AHTTADRA2AKDM4E | |
| SCHEMBL5483517 | 0.79 | ADORA2A (0.60) | HSD17B10ADORA2AHTTADRA2AKDM4E | |
| SCHEMBL5483521 | 0.79 | KDM4E (0.64) | HSD17B10ADORA2AHTTADRA2AKDM4E | |
| SCHEMBL4072588 | 0.78 | SQOR (0.56) | HSD17B10ADORA2AHTTADRA2AKDM4E | |
| SCHEMBL8974906 | 0.78 | HSD17B10 (0.68) | HSD17B10ADORA2AHTTADRA2AKDM4E | |
| SCHEMBL6256113 | 0.78 | HSD17B10 (0.72) | HSD17B10ADORA2AHTTADRA2AKDM4E | |
| SCHEMBL8299115 | 0.77 | KDM4E (0.80) | HSD17B10ADORA2AHTTADRA2AKDM4E | |
| SCHEMBL3372013 | 0.74 | KDM4E (0.69) | HSD17B10ADORA2AHTTADRA2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4508722-A | 1-Benzoyl-3-(arylpyridyl)urea compounds | ELI LILLY AND COMPANY (US) | 1985-04-02 | — | — | US | disclosed |
| US-4405552-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1983-09-20 | — | — | US | disclosed |