Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5483513 | 0.79 | HSD17B10 (0.72) | ADORA2AHSD17B10HTTADRA2AKDM4E | |
| SCHEMBL11037564 | 0.79 | HSD17B10 (0.77) | ADORA2AHSD17B10HTTADRA2AKDM4E | |
| SCHEMBL7094514 | 0.73 | ALDH1A1 (0.55) | ADORA2AHSD17B10HTTADRA2AKDM4E | |
| SCHEMBL5321147 | 0.73 | ADORA1 (0.77) | ADORA2AADORA1 | |
| SCHEMBL5483590 | 0.73 | SQOR (0.56) | ADORA2AHSD17B10HTTADRA2AKDM4E | |
| SCHEMBL12992409 | 0.73 | ALDH1A1 (0.50) | ADORA2AHSD17B10HTTADRA2AKDM4E | |
| SCHEMBL7011406 | 0.73 | ADORA2A (0.70) | ADORA2AHSD17B10HTTADRA2AKDM4E | |
| SCHEMBL11008493 | 0.72 | HTT (0.59) | ADORA2AHSD17B10HTTADRA2AKDM4E | |
| SCHEMBL5482012 | 0.72 | KDM4E (0.58) | ADORA2AHSD17B10HTTADRA2AKDM4E | |
| SCHEMBL22198972 | 0.71 | HSD17B10 (0.53) | ADORA2AHSD17B10HTTADRA2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070287738-A1 | Substituted Cyanopyridines as protein kinase inhibitors | WYETH | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287738-A1 | Substituted Cyanopyridines as protein kinase inhibitors | CNKSR1, MAP3K1, MAP3K6 | ADORA2A 1009/4885HSD17B10 4631/4885HTT 4209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.