Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.68 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.68 |
| ▸ | HTT | P42858 | 3/20 | 0.68 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | FABP3 | P05413 | 1/20 | 0.50 |
| ▸ | FABP4 | P15090 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | PRNP | P04156 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8975579 | 0.86 | ALDH1A1 (0.55) | HSD17B10ADORA2AHTTADRA2AKDM4E | |
| SCHEMBL8918577 | 0.85 | ALDH1A1 (0.72) | HSD17B10ADORA2AHTTADRA2AKDM4E | |
| SCHEMBL8975128 | 0.84 | HTT (0.48) | HSD17B10ADORA2AHTTADRA2AKDM4E | |
| SCHEMBL19356918 | 0.78 | ADORA2A (0.56) | HSD17B10ADORA2AHTTADRA2AKDM4E | |
| SCHEMBL11037564 | 0.78 | HSD17B10 (0.77) | HSD17B10ADORA2AHTTADRA2AKDM4E | |
| SCHEMBL6957371 | 0.77 | SMN1; SMN2 (0.65) | HTTKDM4ERXFP1ALDH1A1HPGD | |
| SCHEMBL7011406 | 0.77 | ADORA2A (0.70) | HSD17B10ADORA2AHTTADRA2AKDM4E | |
| SCHEMBL22866590 | 0.75 | ADORA1 (0.53) | HSD17B10ADORA2AHTTADRA2AALDH1A1 | |
| SCHEMBL29661937 | 0.75 | ADORA1 (0.53) | HSD17B10ADORA2AHTTADRA2AALDH1A1 | |
| SCHEMBL5483513 | 0.75 | HSD17B10 (0.72) | HSD17B10ADORA2AHTTADRA2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705820-A1 | 6-Amino-nicotinic acid derivatives and their use as selective K-channel modulators | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |