Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11041569 | 0.90 | HPGD (0.53) | MEN1KMT2ASMN1; SMN2NPC1HTT | |
| SCHEMBL11043804 | 0.90 | ACHE (0.47) | SIRT2THRBFAAHHPGDLMNA | |
| SCHEMBL11046557 | 0.88 | PSMB5 (0.48) | MEN1KMT2ASIRT2SMN1; SMN2NPC1 | |
| SCHEMBL11042909 | 0.88 | MAPT (0.46) | MEN1KMT2ASIRT2SMN1; SMN2HTT | |
| SCHEMBL11038572 | 0.88 | LMNA (0.53) | MEN1KMT2ASIRT2SMN1; SMN2HTT | |
| SCHEMBL11037929 | 0.88 | SIRT2 (0.55) | MEN1KMT2ASIRT2SMN1; SMN2RAB9A | |
| SCHEMBL11039230 | 0.88 | SIRT2 (0.45) | SIRT2RAB9ALMNATDP1FFAR1 | |
| SCHEMBL9799045 | 0.88 | RAB9A (0.53) | MEN1KMT2ASIRT2SMN1; SMN2NPC1 | |
| SCHEMBL11040156 | 0.87 | EPHX2 (0.41) | SIRT2THRBFAAHHPGDLMNA | |
| SCHEMBL11041771 | 0.87 | RAB9A (0.55) | MEN1KMT2ASIRT2NPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4490165-A | Meta-(phenylalkoxy)phenyl-N-methoxy-N-methylurea compounds, methods for preparing same and herbicidal use thereof | AMERICAN CYANAMID COMPANY (US) | 1984-12-25 | — | — | US | disclosed |
| US-4308213-A | Meta-(phenylalkoxy)phenyl-N-methoxy-N-methylurea compounds | AMERICAN CYANAMID COMPANY (US) | 1981-12-29 | — | — | US | disclosed |