Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | PPID | Q08752 | 4/20 | 0.42 |
| ▸ | PPIB | P23284 | 1/20 | 0.42 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | PPIG | Q13427 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22010661 | 0.83 | GAA (0.41) | GAAEPHX2PPIDPPIBPPIA | |
| SCHEMBL11290272 | 0.82 | GAA (0.44) | GAAEPHX2PPIDPPIBPPIA | |
| SCHEMBL580416 | 0.79 | EPHX2 (0.43) | GAAEPHX2PPIDPPIBPPIA | |
| SCHEMBL1651948 | 0.77 | MME (0.55) | CYP3A4SMN1; SMN2P2RX7ALDH1A1 | |
| SCHEMBL10304246 | 0.76 | DRD2 (0.41) | GAASMN1; SMN2P2RX7ALDH1A1 | |
| SCHEMBL16775484 | 0.75 | GAA (0.52) | GAAEPHX2MGAMSIMGAM2 | |
| SCHEMBL11427402 | 0.74 | EPHX2 (0.40) | GAAEPHX2PPIDPPIBPPIA | |
| SCHEMBL11427404 | 0.74 | EPHX2 (0.40) | GAAEPHX2PPIDPPIBPPIA | |
| SCHEMBL26081876 | 0.74 | ALDH1A1 (0.40) | SMN1; SMN2P2RX7ALDH1A1 | |
| SCHEMBL25857186 | 0.72 | GAA (0.43) | GAAEPHX2PPIDPPIBPPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59196849-A | — | — | None | — | — | JP | disclosed |
| JP-S59196849-A | NOVEL CARBOXYLIC ACID DERIVATIVE | HISAMITSU PHARMACEUT CO INC | 1984-11-08 | — | — | JP | disclosed |