Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | PPID | Q08752 | 4/20 | 0.37 |
| ▸ | PPIB | P23284 | 1/20 | 0.37 |
| ▸ | PPIA | P62937 | 1/20 | 0.37 |
| ▸ | PPIG | Q13427 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4313621 | 0.81 | MME (0.39) | NR1H4 | |
| SCHEMBL11427402 | 0.81 | EPHX2 (0.40) | EPHX2GAAPPIDPPIBPPIA | |
| SCHEMBL11427404 | 0.81 | EPHX2 (0.40) | EPHX2GAAPPIDPPIBPPIA | |
| SCHEMBL1249220 | 0.81 | ALDH1A1 (0.37) | GAA | |
| SCHEMBL4894476 | 0.80 | PRMT1 (0.32) | SMN1; SMN2 | |
| SCHEMBL4897136 | 0.80 | OPRL1 (0.31) | GAA | |
| SCHEMBL11038014 | 0.79 | GAA (0.45) | EPHX2GAAPPIDPPIBPPIA | |
| SCHEMBL4899386 | 0.79 | METAP2 (0.38) | TSHR | |
| SCHEMBL2700331 | 0.77 | BRD4 (0.35) | TSHRSMN1; SMN2 | |
| SCHEMBL2702145 | 0.77 | BRD4 (0.35) | TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210045983-A1 | RETINOL REPLACEMENT IN SKIN TREATMENT | SYMRISE AG (DE) | 2021-02-18 | — | — | US | claimed |
| EP-3773445-A1 | RETINOL REPLACEMENT IN SKIN TREATMENT | Symrise AG (DE) | 2021-02-17 | — | — | EP | claimed |
| WO-2019185923-A1 | RETINOL REPLACEMENT IN SKIN TREATMENT | SYMRISE AG (DE) | 2019-10-03 | — | — | WO | claimed |
| US-20190099342-A1 | COOLING PRODUCT | SYMRISE AG (DE) | 2019-04-04 | — | — | US | claimed |
| US-20180185301-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING POLYALKYLENE GLYCOL DERIVATIVES | SYMRISE AG (DE) | 2018-07-05 | — | — | US | claimed |
| EP-3108941-A1 | COMPOSITIONS COMPRISING POLYALKYLENE GLYCOL DERIVATIVES | Symrise AG (DE) | 2016-12-28 | — | — | EP | claimed |
| EP-2887929-A2 | COMPOUNDS FOR PREVENTING, REDUCING AND/OR ALLEVIATING ITCHY SKIN CONDITION(S) | Symrise AG (DE) | 2015-07-01 | — | — | EP | claimed |
| WO-2012143576-A2 | COMPOUNDS FOR PREVENTING, REDUCING AND/OR ALLEVIATING ITCHY SKIN CONDITION(S) | SYMRISE AG (DE) | 2012-10-26 | — | — | WO | claimed |
| EP-2416766-A2 | COMPOSITIONS COMPRISING TRANS-TERT-BUTYL CYCLOHEXANOL AS SKIN IRRITATION-REDUCING AGENT | Symrise AG (DE) | 2012-02-15 | — | — | EP | claimed |
| WO-2009087242-A2 | COMPOSITIONS COMPRISING TRANS-TERT-BUTYL CYCLOHEXANOL AS SKIN IRRITATION-REDUCING AGENT | SYMRISE GMBH & CO. KG (DE) | 2009-07-16 | — | — | WO | claimed |
| US-20240000746-A1 | New Cooling Agents and Preparations Containing Them | SYMRISE AG (DE) | 2024-01-04 | — | — | US | disclosed |
| US-11801210-B2 | Retinol replacement in skin treatment | SYMRISE AG (DE) | 2023-10-31 | — | — | US | disclosed |
| EP-4247791-A2 | NEW COOLANTS, AND PREPARATIONS CONTAINING SAME | Symrise AG (DE) | 2023-09-27 | — | — | EP | disclosed |
| US-20230190633-A1 | A WHEAT BRAN EXTRACT IN A HAIR CARE BLEND | SYMRISE AG (DE) | 2023-06-22 | — | — | US | disclosed |
| US-11596150-B2 | Long chain glycolipids useful to avoid perishing or microbial contamination of materials | IMD NATURAL SOLUTIONS GMB (DE) | 2023-03-07 | — | — | US | disclosed |
| EP-2416766-A2 | COMPOSITIONS COMPRISING TRANS-TERT-BUTYL CYCLOHEXANOL AS SKIN IRRITATION-REDUCING AGENT | Symrise AG (DE) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010149798-A2 | USE OF POLYOLS FOR ENHANCING THE COOLING EFFECT OF A COOLING SUBSTANCE AND COOLING MIXTURES HAVING AN ENHANCED COOLING EFFECT | SYMRISE AG (DE) | 2010-12-29 | — | — | WO | disclosed |
| WO-2009087242-A2 | COMPOSITIONS COMPRISING TRANS-TERT-BUTYL CYCLOHEXANOL AS SKIN IRRITATION-REDUCING AGENT | SYMRISE GMBH & CO. KG (DE) | 2009-07-16 | — | — | WO | disclosed |
| US-20080175800-A1 | USE OF SPECIFIC MENTHYL 3-OXOCARBOXYLIC ACID ESTERS AS PHYSIOLOGICALLY ACTIVE COOLING SUBSTANCES | SYMRISE GMBH & CO. KG (DE) | 2008-07-24 | — | — | US | disclosed |
| US-20080096969-A1 | N alpha-(Menthanecarbonyl)amino acid amides and use thereof as physiological cooling active ingredients | SYMRISE GMBH & CO. KG (DE) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11596150-B2 | Long chain glycolipids useful to avoid perishing or microbial contamination of materials | LPO, PLIN1, PLIN3 | EPHX2 3114/4885GAA 566/4885PPID 2316/4885 |
| US-20190099342-A1 | COOLING PRODUCT | TRPA1, TRPV2, NISCH | EPHX2 2306/4885GAA 1830/4885PPID 1589/4885 |
| US-20210045983-A1 | RETINOL REPLACEMENT IN SKIN TREATMENT | RBP1, RBP4, LRAT | EPHX2 1089/4885GAA 1493/4885PPID 1758/4885 |
| US-11801210-B2 | Retinol replacement in skin treatment | RBP1, RBP4, LRAT | EPHX2 1124/4885GAA 1295/4885PPID 1516/4885 |
| US-20240000746-A1 | New Cooling Agents and Preparations Containing Them | TTPA, TREH, TAS2R45 | EPHX2 1975/4885GAA 2325/4885PPID 3040/4885 |
| US-20180185301-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING POLYALKYLENE GLYCOL DERIVATIVES | PARG, PARN, TRPV1 | EPHX2 467/4885GAA 3560/4885PPID 1166/4885 |
| US-20080096969-A1 | N alpha-(Menthanecarbonyl)amino acid amides and use thereof as physiological cooling active ingredients | NMBR, RIMKLA, NAAA | EPHX2 2541/4885GAA 2266/4885PPID 888/4885 |
| US-20080175800-A1 | USE OF SPECIFIC MENTHYL 3-OXOCARBOXYLIC ACID ESTERS AS PHYSIOLOGICALLY ACTIVE COOLING SUBSTANCES | ECI1, OTC, MDH2 | EPHX2 116/4885GAA 3669/4885PPID 817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.