SCHEMBL11038280

SCHEMBL11038280

N#CC1(CCNC(=O)C(Cl)Cl)CCCCC1

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A2 O94788 1/20 0.42
ALDH1A1 P00352 1/20 0.42
ALDH2 P05091 1/20 0.42
ALDH1A3 P47895 1/20 0.42
P2RX7 Q99572 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11039996 0.92 ALDH1A2 (0.46) ALDH1A2ALDH1A1ALDH2ALDH1A3
SCHEMBL21997570 0.75 KDM1A (0.32) P2RX7
SCHEMBL2154404 0.69 ALDH1A1 (0.43) ALDH1A1
SCHEMBL11258952 0.68 RXFP1 (0.44)
SCHEMBL11252123 0.68 RXFP1 (0.44)
SCHEMBL11251570 0.68 RXFP1 (0.44)
SCHEMBL3840377 0.67 ALDH1A1 (0.33) ALDH1A1
SCHEMBL11252268 0.66 RXFP1 (0.42)
SCHEMBL16419574 0.63 ALDH1A1 (0.39) ALDH1A1
SCHEMBL840651 0.63 CYP2C19 (0.48) ALDH1A1P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0025345-B1 N-CYANOALKYL HALOACETAMIDES, PREPARATION THEREOF, USE THEREOF AS HERBICIDE ANTIDOTES AND COMPOSITIONS COMPRISING SAME STAUFFER CHEMICAL COMPANY (US) 1984-02-29 EP disclosed
US-4335053-A HERBICIDES STAUFFER CHEMICAL COMPANY (US) 1982-06-15 US disclosed
US-4288384-A N-Cyanoalkyl haloacetamides herbicidal antidotes STAUFFER CHEMICAL COMPANY (US) 1981-09-08 US disclosed
EP-0025345-A1 N-cyanoalkyl haloacetamides, preparation thereof, use thereof as herbicide antidotes and compositions comprising same STAUFFER CHEMICAL COMPANY (US) 1981-03-18 EP disclosed