Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3495245 | 1.00 | CYP2C19 (0.48) | CYP2C19ALDH1A1CYP1A2USP2LMNA | |
| SCHEMBL3909670 | 0.98 | CYP2C19 (0.47) | CYP2C19ALDH1A1CYP1A2USP2LMNA | |
| SCHEMBL2805815 | 0.98 | CYP2C19 (0.45) | CYP2C19ALDH1A1CYP1A2USP2LMNA | |
| SCHEMBL2807409 | 0.93 | HSD11B1 (0.41) | CYP2C19ALDH1A1CYP1A2USP2LMNA | |
| SCHEMBL7552932 | 0.89 | — | — | |
| SCHEMBL5692544 | 0.81 | ALDH1A1 (0.38) | CYP2C19ALDH1A1CYP1A2USP2LMNA | |
| SCHEMBL8839908 | 0.79 | ALDH1A1 (0.37) | CYP2C19ALDH1A1CYP1A2USP2LMNA | |
| Potassium Ion SCHEMBL3909671 | 0.79 | ALDH1A1 (0.37) | CYP2C19ALDH1A1CYP1A2USP2LMNA | |
| SCHEMBL14744077 | 0.78 | MCL1 (0.36) | CYP2C19ALDH1A1CYP1A2USP2LMNA | |
| SCHEMBL31119581 | 0.76 | P2RX7 (0.38) | CYP2C19ALDH1A1CYP1A2USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12428656-B2 | Nitrilase mutant and application thereof in the synthesis of 1-cyanocyclohexyl acetic acid | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2025-09-30 | — | — | US | claimed |
| US-20250084395-A1 | ENGINEERED NITRILASES FOR BIOCATALYSIS | KCAT ENZYMATIC PRIVATE LIMITED (IN) | 2025-03-13 | — | — | US | claimed |
| WO-2025041039-A1 | IMMOBILISED WHOLE CELL NITRILASES FOR BIOCATALYSIS OF GABAPENTIN INTERMEDIATE | GRANULES INDIA LIMITED (IN) | 2025-02-27 | — | — | WO | claimed |
| CN-118931887-A | Nitrilase cross-linked enzyme aggregate, and preparation method and application thereof | 浙江工业大学 | 2024-11-12 | — | — | CN | claimed |
| CN-118440142-A | Connecting peptide, nitrilase fusion protein and application thereof | 浙江工业大学 | 2024-08-06 | — | — | CN | claimed |
| CN-118341476-A | Porous Raney nickel base alloy catalyst, preparation method and application thereof in low-temperature hydrogenation reaction | 浙江工业大学 | 2024-07-16 | — | — | CN | claimed |
| CN-113025601-B | Optimized expression and application of nitrilase promoter | 上海奥博生物医药股份有限公司 | 2024-06-21 | — | — | CN | claimed |
| CN-118086272-A | High-efficiency nitrilase immobilization method and application | 浙江工业大学 | 2024-05-28 | — | — | CN | claimed |
| US-11987826-B2 | Nitrilase mutant and application thereof in the synthesis of an anti-epileptic drug intermediate | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2024-05-21 | — | — | US | claimed |
| CN-114958801-B | Product tolerant nitrilase mutant and application thereof | 浙江工业大学 | 2024-05-03 | — | — | CN | claimed |
| EP-2024324-A1 | PROCESS FOR PREPARING GABAPENTIN | Pfizer Science and Technology Ireland Limited (IE) | 2009-02-18 | — | — | EP | claimed |
| WO-2008004115-A1 | PROCESS FOR PREPARING GABAPENTIN | ZACH SYSTEM S.P.A. (IT) | 2008-01-10 | — | — | WO | claimed |
| WO-2007129286-A1 | PROCESS FOR PREPARING GABAPENTIN | PFIZER SCIENCE AND TECHNOLOGY IRELAND LIMITED (IE) | 2007-11-15 | — | — | WO | claimed |
| EP-1639118-A1 | BIOCATALYTIC PREPARATION OF 1-CYANOCYCLOHEXANEACETIC ACID | Pfizer Products Inc. (US) | 2006-03-29 | — | — | EP | claimed |
| US-20050009154-A1 | Biocatalytic preparation of 1-cyano-cyclohexaneacetic acid | PFIZER INC | 2005-01-13 | — | — | US | claimed |
| WO-2004111256-A1 | BIOCATALYTIC PREPARATION OF 1-CYANOCYCLOHEXANEACETIC ACID | PFIZER PRODUCTS INC. (US) | 2004-12-23 | — | — | WO | claimed |
| US-5693845-A | Cyanocycloalkylacetic acid and ester intermediates for preparing cyclic amino acid anticonvulsant compounds | WARNER-LAMBERT COMPANY (US) | 1997-12-02 | — | — | US | claimed |
| EP-0414262-B1 | Process for the preparation of cyclic amino anticonvulsant compounds | WARNER LAMBERT CO (US) | 1994-11-30 | — | — | EP | claimed |
| US-5132451-A | Process for cyclic amino acid anticonvulsant compounds | WARNER-LAMBERT COMPANY (US) | 1992-07-21 | — | — | US | claimed |
| EP-0414262-A2 | Process for the preparation of cyclic amino anticonvulsant compounds | WARNER-LAMBERT COMPANY (US) | 1991-02-27 | — | — | EP | claimed |