Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11038280 | 0.75 | ALDH1A2 (0.42) | P2RX7 | |
| SCHEMBL31124660 | 0.75 | LMNA (0.32) | KDM1A | |
| SCHEMBL25317589 | 0.72 | KDM1A (0.37) | KDM1AP2RX7 | |
| SCHEMBL2807409 | 0.70 | HSD11B1 (0.41) | KDM1A | |
| SCHEMBL17446963 | 0.69 | ALDH1A1 (0.35) | — | |
| SCHEMBL21998137 | 0.68 | USP2 (0.46) | — | |
| SCHEMBL11606982 | 0.67 | CYP2D6 (0.31) | — | |
| SCHEMBL31124625 | 0.67 | CYP1A2 (0.38) | — | |
| SCHEMBL15140431 | 0.66 | CYP2D6 (0.30) | — | |
| SCHEMBL2805815 | 0.66 | CYP2C19 (0.45) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3886904-A1 | IRAK DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020113233-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-06-04 | — | — | WO | disclosed |