Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.71 |
| ▸ | RAB9A | P51151 | 8/20 | 0.71 |
| ▸ | MAPT | P10636 | 8/20 | 0.71 |
| ▸ | NPC1 | O15118 | 7/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.71 |
| ▸ | PKM | P14618 | 1/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 5/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.51 |
| ▸ | CLK1 | P49759 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11136424 | 0.79 | MAPT (0.68) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL10544279 | 0.78 | MEN1 (0.61) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL10519545 | 0.77 | MAPT (0.44) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL11038508 | 0.75 | NPC1 (0.72) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL11042883 | 0.75 | NPC1 (0.72) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL22761299 | 0.75 | MAPT (0.64) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL13955047 | 0.75 | MAPT (0.59) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL10520554 | 0.75 | RAB9A (0.49) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL24101694 | 0.75 | MEN1 (0.57) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL9832616 | 0.75 | MEN1 (0.63) | MEN1KMT2ARAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0052564-B1 | DERIVATIVES OF 2-THIAZOLYL-OXAMIC ACID SUBSTITUTED IN POSITION 4 BY A THIENYL OR FURYL RADICAL, THEIR PREPARATION AND USE AS PHARMACEUTICAL PREPARATIONS | PIERRE FABRE S.A. (FR) | 1984-10-17 | — | — | EP | claimed |