Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7638491 | 0.89 | SMN1; SMN2 (0.37) | ESR1MEN1KMT2ANPSR1 | |
| SCHEMBL7636019 | 0.86 | TSHR (0.43) | ESR1MEN1KMT2AHPGDGFER | |
| SCHEMBL11039782 | 0.83 | ALDH1A1 (0.39) | MEN1KMT2AHPGDGFERNPSR1 | |
| SCHEMBL11044031 | 0.81 | RAD52 (0.41) | MEN1KMT2ATDP1ALDH1A1LMNA | |
| SCHEMBL11042269 | 0.81 | ALDH1A1 (0.37) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL6850422 | 0.80 | ESR1 (0.48) | ESR1MEN1KMT2AHPGDGFER | |
| SCHEMBL6302960 | 0.80 | ESR1 (0.48) | ESR1MEN1KMT2AHPGDGFER | |
| SCHEMBL11045681 | 0.80 | SMN1; SMN2 (0.52) | KMT2ATDP1ALDH1A1GAAMAPT | |
| SCHEMBL11041392 | 0.79 | TSHR (0.46) | ESR1CNR2KDM4EGAALMNA | |
| SCHEMBL107013 | 0.79 | CNR2 (0.49) | ESR1MEN1KMT2AHPGDGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4430259-A | Water-soluble disazo compounds suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-02-07 | — | — | US | disclosed |
| US-4283196-A | FIXING BY ACTION OF AN ALKALINE AGENT | AMERICAN HOECHST CORPORATION (US) | 1981-08-11 | — | — | US | disclosed |
| US-4271072-A | FIBER-REACTIVE, FOR DYEING NATURAL AND SYNTHETIC POLYAMIDES AND CELULOSES | AMERICAN HOECHST CORPORATION (US) | 1981-06-02 | — | — | US | disclosed |