Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7638491 | 0.89 | SMN1; SMN2 (0.37) | TSHRCYP2C19ESR1SMN1; SMN2HSP90AA1 | |
| SCHEMBL11039782 | 0.83 | ALDH1A1 (0.39) | CYP2C19LMNABLMSMN1; SMN2HSP90AA1 | |
| SCHEMBL7636019 | 0.83 | TSHR (0.43) | TSHRCYP2C19ESR1GLASMN1; SMN2 | |
| SCHEMBL11042269 | 0.80 | ALDH1A1 (0.37) | TSHRCYP2C19CYP2D6LMNAPMP22 | |
| SCHEMBL11695114 | 0.80 | KDM1A (0.39) | NR3C1CRHBPCRHR2 | |
| SCHEMBL11042253 | 0.79 | MAPK1 (0.33) | CYP2C19SMN1; SMN2HSP90AA1 | |
| SCHEMBL11038710 | 0.79 | ESR1 (0.45) | ESR1LMNACNR2KDM4ENR1H2 | |
| SCHEMBL11042584 | 0.79 | CA12 (0.34) | CYP2C19SMN1; SMN2HSP90AA1CA2GAA | |
| SCHEMBL10655752 | 0.79 | TSHR (0.50) | TSHRCYP2C19NR3C1ESR1CYP2D6 | |
| SCHEMBL11044031 | 0.78 | RAD52 (0.41) | TSHRCYP2C19CYP2D6MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4430259-A | Water-soluble disazo compounds suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-02-07 | — | — | US | disclosed |