Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7638491 | 0.91 | SMN1; SMN2 (0.37) | SMN1; SMN2TSHRMEN1CYP3A4CYP2C9 | |
| SCHEMBL11039782 | 0.84 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL11045681 | 0.84 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2MAPTLTA4HKMT2A | |
| SCHEMBL11044031 | 0.82 | RAD52 (0.41) | ALDH1A1SMN1; SMN2LMNACYP2D6TSHR | |
| SCHEMBL2804456 | 0.82 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2GMNNLMNACYP2D6 | |
| SCHEMBL7636019 | 0.81 | TSHR (0.43) | ALDH1A1SMN1; SMN2MAPTTSHRHTT | |
| SCHEMBL11038710 | 0.81 | ESR1 (0.45) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL11041392 | 0.80 | TSHR (0.46) | SMN1; SMN2LMNACYP2D6TSHRPMP22 | |
| SCHEMBL10794428 | 0.80 | ALDH1A1 (0.40) | ALDH1A1TBXA2RSMN1; SMN2GMNNLMNA | |
| SCHEMBL7641411 | 0.79 | USP2 (0.45) | ALDH1A1SMN1; SMN2LMNAHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4430259-A | Water-soluble disazo compounds suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-02-07 | — | — | US | disclosed |
| US-4283196-A | FIXING BY ACTION OF AN ALKALINE AGENT | AMERICAN HOECHST CORPORATION (US) | 1981-08-11 | — | — | US | disclosed |
| US-4271072-A | FIBER-REACTIVE, FOR DYEING NATURAL AND SYNTHETIC POLYAMIDES AND CELULOSES | AMERICAN HOECHST CORPORATION (US) | 1981-06-02 | — | — | US | disclosed |