Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11039782 | 0.93 | ALDH1A1 (0.39) | SMN1; SMN2MEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11042269 | 0.91 | ALDH1A1 (0.37) | SMN1; SMN2MEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7636019 | 0.90 | TSHR (0.43) | SMN1; SMN2MEN1CYP2C9CYP2C19KMT2A | |
| SCHEMBL11038710 | 0.89 | ESR1 (0.45) | MEN1KMT2AESR1NPSR1 | |
| SCHEMBL11041392 | 0.89 | TSHR (0.46) | SMN1; SMN2CYP2C19HSP90AA1TSHRCA2 | |
| SCHEMBL11044031 | 0.88 | RAD52 (0.41) | SMN1; SMN2MEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7641411 | 0.88 | USP2 (0.45) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11042584 | 0.86 | CA12 (0.34) | SMN1; SMN2MEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11042253 | 0.86 | MAPK1 (0.33) | SMN1; SMN2MEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11045681 | 0.83 | SMN1; SMN2 (0.52) | SMN1; SMN2KMT2APPARGMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6464734-B1 | USED FOR DYEING OR PRINTING HYDROXYL AND/OR CARBOXAMIDO CONTAINING MATERIALS SUCH AS POLYVINYL ALCOHOL, POLYURETHANES AND POLYAMIDES; WASHFASTNESS | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2002-10-15 | — | — | US | disclosed |
| EP-1134260-A1 | Deep black dye mixtures of fiber-reactive azo dyes | DyStar Textilfarben GmbH & Co. Deutschland KG (DE) | 2001-09-19 | — | — | EP | disclosed |
| US-6177552-B1 | CONTAINING (((VINYLSULFONYL)ALKYLAMINO)ALKYLSULFONYL)PHENYLAZO GROUPS | DYSTARTEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2001-01-23 | — | — | US | disclosed |
| US-5216138-A | With vinyl sulfonyl group | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-01 | — | — | US | disclosed |
| US-5043435-A | Fiber-reactive benzotriazolyl-phenyl diazonium compounds suitable as diazo compounds for the preparation of azo dyes, and process for preparing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-27 | — | — | US | disclosed |
| US-5037449-A | For dyeing or printing cotton or wool | CIBA-GEIGY CORPORATION (US) | 1991-08-06 | — | — | US | disclosed |
| US-5021559-A | Water-soluble azo compounds containing a fiber-reactive group of the vinylsulfone series, suitable as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-06-04 | — | — | US | disclosed |
| US-5010180-A | Printing, dyeing | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-23 | — | — | US | disclosed |
| US-4968781-A | COTTON | CIBA-GEIGY CORPORATION (US) | 1990-11-06 | — | — | US | disclosed |
| US-4952679-A | PRINTING, DYEING CELLULOSE | CIBA-GEIGY CORPORATION (US) | 1990-08-28 | — | — | US | disclosed |
| US-4946947-A | Water-soluble azo compounds containing a benzotiazol-1-yl phenyl moiety as a diazo component which carry a fiber-reactive group of the vinylsulfone series | SPRINGER HARTMUT (DE) | 1990-08-07 | — | — | US | disclosed |
| US-4929719-A | Fiber-reactive dyes containing an aniline radical which carries two different vinylsulfonyl moieties | CIBA-GEIGY CORPORATION (US) | 1990-05-29 | — | — | US | disclosed |
| US-4918169-A | COTTON | CIBA-GEIGY CORPORATION (US) | 1990-04-17 | — | — | US | disclosed |
| US-4564672-A | Water-soluble monoazo and disazo compounds containing a fibre-reactive 2-alkoxy-5-chloro-aniline diazo component and copper complexes thereof, useful as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-01-14 | — | — | US | disclosed |