Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.56 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.54 |
| ▸ | ANPEP | P15144 | 1/20 | 0.52 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.52 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | CCR3 | P51677 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27632879 | 0.92 | SOAT1 (0.54) | SCN9ASOAT1ALDH1A1HTTNCOA1 | |
| SCHEMBL27632878 | 0.92 | SOAT1 (0.54) | SCN9ASOAT1ALDH1A1HTTNCOA1 | |
| SCHEMBL27653259 | 0.92 | SOAT1 (0.54) | SCN9ASOAT1ALDH1A1HTTNCOA1 | |
| SCHEMBL14338268 | 0.82 | ALDH1A1 (0.62) | SOAT1ALDH1A1HTTNCOA1SMN1; SMN2 | |
| SCHEMBL2185269 | 0.82 | LTA4H (0.64) | LTA4H | |
| SCHEMBL29519583 | 0.82 | LTA4H (0.64) | LTA4H | |
| SCHEMBL1864709 | 0.82 | LTA4H (0.64) | LTA4H | |
| SCHEMBL28860411 | 0.82 | LTA4H (0.64) | LTA4H | |
| SCHEMBL27517670 | 0.82 | LTA4H (0.64) | LTA4H | |
| SCHEMBL7317027 | 0.81 | LARS1 (0.56) | SCN9AALDH1A1ANPEPRNPEPDNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479941-A | TREATMENT OF HYPERTENSION AND HYPERALDOSTERONISM | MERCK & CO., INC. (US) | 1984-10-30 | — | — | US | disclosed |