Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LARS1 | Q9P2J5 | 3/20 | 0.56 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.44 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7657880 | 1.00 | LARS1 (0.56) | LARS1SCN9ALMNAALDH1A1TSHR | |
| SCHEMBL7370114 | 0.86 | SLC6A9 (0.49) | LARS1SCN9ALMNAALDH1A1TSHR | |
| SCHEMBL7307439 | 0.83 | CTSC (0.55) | LMNATSHRPOLBMEN1KMT2A | |
| SCHEMBL7307442 | 0.83 | CTSC (0.55) | LMNATSHRPOLBMEN1KMT2A | |
| SCHEMBL9116086 | 0.82 | LTA4H (0.45) | LMNATSHRMMP9MMP8LTA4H | |
| SCHEMBL7316402 | 0.81 | CTRB1 (0.63) | LMNATSHRCTRB1MEN1KMT2A | |
| SCHEMBL11038909 | 0.81 | SCN9A (0.56) | SCN9AALDH1A1LTA4HANPEPRNPEP | |
| SCHEMBL7319572 | 0.80 | CNR1 (0.60) | LARS1ANPEPRNPEPDNPEPCASR | |
| SCHEMBL7666024 | 0.80 | CNR1 (0.60) | LARS1ANPEPRNPEPDNPEPCASR | |
| Leucine SCHEMBL28317734 | 0.79 | SLC7A5 (0.56) | LARS1LMNAALDH1A1LTA4HMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| US-5877277-A | ANTIPROLIFERATIVE/ANTICARCINOGENIC/ANTITUMOR AGENTS WITH MODIFIED AMINO ACIDS FOR COMPETITIVE INHIBITION OF NATURALLY OCCURING PEPTIDE BY BINDING TO RECEPTORS; TREATMENT OF GASTROINTESTINAL DISORDERS | BIOMEASURE, INC. (US) | 1999-03-02 | — | — | US | disclosed |
| US-5750646-A | ANTICARCINOGENIC AGENTS; ANTIINFLAMMATORY AGENTS | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 1998-05-12 | — | — | US | disclosed |
| US-5736517-A | ADMINISTERING TO TREAT COLON, PROSTATE OR BREAST CANCER | BIOMEASURE, INC. (US) | 1998-04-07 | — | — | US | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |