SCHEMBL27653259

SCHEMBL27653259

Cc1ccc(C[C@@H](NC(=O)[C@@H](N)CC(C)C)c2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 1/20 0.54
SCN9A Q15858 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
NFKB1 P19838 1/20 0.47
THPO P40225 1/20 0.47
BLM P54132 1/20 0.47
PMP22 Q01453 1/20 0.47
PSMB5 P28074 1/20 0.47
LARS1 Q9P2J5 1/20 0.46
ALDH1A1 P00352 1/20 0.46
HTT P42858 1/20 0.46
NCOA1 Q15788 1/20 0.46
NCOA3 Q9Y6Q9 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27632878 1.00 SOAT1 (0.54) SOAT1SCN9ASMN1; SMN2CYP1A2CYP2D6
SCHEMBL27632879 1.00 SOAT1 (0.54) SOAT1SCN9ASMN1; SMN2CYP1A2CYP2D6
SCHEMBL11038909 0.92 SCN9A (0.56) SOAT1SCN9ASMN1; SMN2ALDH1A1HTT
SCHEMBL14380840 0.78 SMN1; SMN2 (0.55) SOAT1SMN1; SMN2CYP1A2CYP2D6CYP2C9
SCHEMBL4590876 0.78 SOAT1 (0.53) SOAT1SMN1; SMN2CYP1A2CYP2D6CYP2C9
SCHEMBL7657880 0.77 LARS1 (0.56) SCN9ALARS1ALDH1A1
SCHEMBL7317027 0.77 LARS1 (0.56) SCN9ALARS1ALDH1A1
SCHEMBL14338268 0.75 ALDH1A1 (0.62) SOAT1SMN1; SMN2ALDH1A1HTTNCOA1
SCHEMBL29519583 0.75 LTA4H (0.64)
SCHEMBL2185269 0.75 LTA4H (0.64)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100448881-C Novel chemical bonding chiral immobile phase and its preparation method and uses UNIV CHINA AGRICULTURAL (CN) 2009-01-07 CN disclosed
CN-1800192-A Novel chemical bonding chiral immobile phase and its preparation method and uses UNIV CHINA AGRICULTURAL (CN) 2006-07-12 CN disclosed