Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11041512 | 0.90 | HPGD (0.40) | HPGDCYP2C19ALDH1A1MAPTNT5E | |
| SCHEMBL11043303 | 0.75 | CTDSP1 (0.41) | PLAUHPGDCYP2C19ALDH1A1MAPT | |
| SCHEMBL11039263 | 0.69 | ALDH1A1 (0.37) | HPGDCYP2C19NSD2CASP6ALDH1A1 | |
| SCHEMBL8411722 | 0.67 | PLAU (0.53) | PLAUHPGDCYP2C19NSD2DUSP3 | |
| SCHEMBL28574517 | 0.67 | PLAU (0.59) | PLAUHPGDCYP2C19NSD2DUSP3 | |
| SCHEMBL31634586 | 0.67 | PLAU (0.53) | PLAUHPGDCYP2C19NSD2DUSP3 | |
| SCHEMBL9614835 | 0.66 | CYP4F2 (0.60) | CYP2C19 | |
| SCHEMBL18892727 | 0.65 | MTNR1A (0.50) | MTNR1A | |
| SCHEMBL2131234 | 0.65 | TKT (0.41) | ALDH1A1MAPT | |
| SCHEMBL9713733 | 0.64 | PLAU (0.50) | PLAUHPGDCYP2C19NSD2DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472308-A | Azo dyestuffs containing an amino or acylated amino naphthol monosulfonic acid radical and at least one reactive phosphoric or phosphonic acid group | ICI UNITED STATES, INC. (US) | 1984-09-18 | — | — | US | disclosed |
| US-4230618-A | CELLULOSE | ICI UNITED STATES, INC. (US) | 1980-10-28 | — | — | US | disclosed |