Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27565927 | 0.74 | TSHR (0.41) | ALDH1A1HPGDTSHRHSD17B10KDM4E | |
| SCHEMBL27501902 | 0.71 | CYP4F2 (0.56) | ALDH1A1CYP3A4HSD17B10CYP1A2CYP2D6 | |
| SCHEMBL27414115 | 0.70 | HSD17B10 (0.41) | ALDH1A1HPGDTSHRHSD17B10KDM4E | |
| SCHEMBL27831060 | 0.70 | MTNR1A (0.44) | MEN1KMT2AMPOIAPPMTNR1A | |
| Hydrochloric Acid SCHEMBL27541293 | 0.69 | MTNR1A (0.43) | MEN1KMT2AMPOIAPPMTNR1A | |
| SCHEMBL6670265 | 0.69 | MEN1 (0.47) | CYP1A2SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL11039149 | 0.69 | PLAU (0.38) | ALDH1A1HPGDCYP2C19MAPTCASP6 | |
| SCHEMBL5674154 | 0.68 | ALDH1A1 (0.48) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL11041512 | 0.67 | HPGD (0.40) | ALDH1A1HPGDCYP2C19MAPTIAPP | |
| SCHEMBL8416393 | 0.66 | ALDH1A1 (0.62) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472308-A | Azo dyestuffs containing an amino or acylated amino naphthol monosulfonic acid radical and at least one reactive phosphoric or phosphonic acid group | ICI UNITED STATES, INC. (US) | 1984-09-18 | — | — | US | disclosed |