Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 4/20 | 0.49 |
| ▸ | CES1 | P23141 | 3/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | PTGFR | P43088 | 1/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1206928 | 0.89 | MAPT (0.66) | NAAAMAPTRXFP1FAAHHDAC6 | |
| SCHEMBL5308357 | 0.88 | FFAR1 (0.52) | TAAR1FFAR1 | |
| SCHEMBL1205707 | 0.87 | MAPT (0.62) | NAAAMAPTRXFP1TAAR1HDAC6 | |
| SCHEMBL19612566 | 0.84 | NAAA (0.55) | NAAAMAPTRXFP1FAAHCES1 | |
| SCHEMBL8511630 | 0.83 | MAPT (0.71) | MAPTRXFP1FAAHCES1HDAC6 | |
| SCHEMBL315728 | 0.81 | SLC6A3 (0.63) | NAAAMAPTRXFP1TAAR1HDAC6 | |
| SCHEMBL3270086 | 0.81 | MAPT (0.68) | MAPTRXFP1FAAHCES1HDAC6 | |
| SCHEMBL11037045 | 0.81 | PLAAT3 (0.58) | NAAAMAPTRXFP1FAAHTAAR1 | |
| SCHEMBL11038837 | 0.80 | HDAC1 (0.58) | MAPTRXFP1FAAHCES1TAAR1 | |
| SCHEMBL11041817 | 0.80 | HDAC1 (0.58) | MAPTRXFP1FAAHCES1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038343-B1 | SUBSTITUTED CARBOXYLIC CETO-ACIDS, PROCESS FOR THE PREPARATION THEREOF, USE THEREOF AND MEDICINAL COMPOSITIONS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1984-12-27 | — | — | EP | disclosed |
| US-4334089-A | HYPOGLYCEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT (DE) | 1982-06-08 | — | — | US | disclosed |