SCHEMBL11039732

SCHEMBL11039732

O=C1CCC(=O)N1C1C=CCCC1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
HPGD P15428 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35
OPRM1 P35372 2/20 0.32
OPRK1 P41145 2/20 0.32
OPRL1 P41146 2/20 0.32
OPRD1 P41143 1/20 0.32
SLC2A1 P11166 1/20 0.31
NOTUM Q6P988 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9789836 0.94 OPRL1 (0.36) ALDH1A1HPGDAPOBEC3GOPRM1OPRK1
SCHEMBL9280282 0.73 OPRM1 (0.39) ALDH1A1OPRM1OPRK1OPRL1NOTUM
SCHEMBL9279862 0.73 OPRM1 (0.39) ALDH1A1OPRM1OPRK1OPRL1NOTUM
SCHEMBL9789955 0.73 OPRM1 (0.34) ALDH1A1OPRM1OPRK1OPRL1OPRD1
SCHEMBL30449036 0.73 ALDH1A1 (0.42) ALDH1A1HPGDAPOBEC3GOPRM1OPRK1
SCHEMBL1571637 0.73 ALDH1A1 (0.42) ALDH1A1HPGDAPOBEC3GOPRM1OPRK1
SCHEMBL250230 0.73 ALDH1A1 (0.42) ALDH1A1HPGDAPOBEC3GOPRM1OPRK1
SCHEMBL23859814 0.73 NOTUM (0.33) OPRM1OPRK1OPRL1NOTUM
SCHEMBL25360239 0.72 OPRM1 (0.38) ALDH1A1HPGDAPOBEC3GOPRM1OPRK1
SCHEMBL15974226 0.71 LMNA (0.41) ALDH1A1HPGDAPOBEC3GOPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59225101-A None JP disclosed
JP-59231068-A None JP disclosed
JP-S59231068-A ACID AMIDE COMPOUND AND ITS PREPARATION SUMITOMO CHEM CO LTD 1984-12-25 JP disclosed
JP-S59225101-A SOIL BLIGHT CONTROLLING AGENT SUMITOMO CHEM CO LTD 1984-12-18 JP disclosed