Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.57 |
| ▸ | DRD3 | P35462 | 4/20 | 0.57 |
| ▸ | DRD4 | P21917 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10894722 | 0.91 | DRD2 (0.63) | DRD2DRD3DRD4 | |
| SCHEMBL10639140 | 0.84 | DRD2 (0.58) | DRD2DRD3DRD4 | |
| SCHEMBL11042681 | 0.81 | DRD2 (0.62) | DRD2DRD3DRD4 | |
| SCHEMBL2218622 | 0.79 | DRD2 (0.82) | DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL9355015 | 0.78 | DRD2 (0.81) | DRD2DRD3DRD4 | |
| SCHEMBL8315422 | 0.78 | HTR1A (0.53) | DRD2DRD3 | |
| SCHEMBL10895464 | 0.77 | ALDH1A1 (0.58) | DRD2DRD3DRD4 | |
| SCHEMBL29383922 | 0.75 | ALDH1A1 (0.65) | DRD2DRD3DRD4 | |
| SCHEMBL8891564 | 0.75 | DRD2 (0.75) | DRD2DRD3DRD4 | |
| Bromide SCHEMBL10894914 | 0.74 | DRD2 (0.66) | DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442126-A | PARKINSON*S DISEASE, CARDIOVASCULAR DISORDERS | SYNTHELABO (FR) | 1984-04-10 | — | — | US | disclosed |