Propene

Propene

SCHEMBL11040490

C=CC.CN(CC(=O)O)C(N)=O

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MVD P53602 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
EYA2 O00167 1/20 0.32
APP P05067 1/20 0.32
ACE P12821 1/20 0.32
TSHR P16473 2/20 0.31
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31
CHRM2 P08172 1/20 0.31
ADRA2A P08913 1/20 0.31
ALOX15 P16050 1/20 0.31
DRD1 P21728 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
CYP2C19 P33261 1/20 0.31
ADRA1A P35348 1/20 0.31
DRD3 P35462 1/20 0.31
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31
SLC6A3 Q01959 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1768268 0.89
Hydrochloric Acid SCHEMBL28825414 0.86 TDP1 (0.38) MVDTDP1EYA2APPACE
SCHEMBL13176709 0.75
SCHEMBL1535475 0.73 LMNA (0.35) MVDTDP1EYA2APPACE
SCHEMBL5662442 0.72 MAOA (0.32)
Acrylamide SCHEMBL27690630 0.71 ALDH1A1 (0.50) TSHRALDH1A1FGFR4
SCHEMBL4556950 0.70
Creatine SCHEMBL21567 0.70
Creatine SCHEMBL27979093 0.70 NOS3 (0.46) MVDTDP1EYA2APPACE
Creatine SCHEMBL30063981 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0154269-A2 Nucleosidetriphosphate-dependent 1-methyl-hydantoinase and its use Roche Diagnostics GmbH (DE) 1985-09-11 EP disclosed