SCHEMBL11040950

SCHEMBL11040950

C=CCC(C)(C=C)C(=O)CCC

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
FFAR3 O14843 2/20 0.31
HDAC3 O15379 2/20 0.31
HDAC1 Q13547 2/20 0.31
HDAC2 Q92769 2/20 0.31
HDAC8 Q9BY41 2/20 0.31
TSHR P16473 2/20 0.31
FAAH O00519 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11043531 0.83 ALDH1A1 (0.36) TSHR
SCHEMBL11040926 0.74 CES2 (0.31) CES2CES1FFAR3HDAC3HDAC1
SCHEMBL11046050 0.74 ALDH1A1 (0.33) TSHR
SCHEMBL11039115 0.73 CES2 (0.30) CES2CES1
SCHEMBL11040838 0.71 ALDH1A1 (0.32) TSHR
SCHEMBL11040831 0.71 ALDH1A1 (0.32) TSHR
SCHEMBL11740552 0.69 MAPT (0.39) TSHR
SCHEMBL28929742 0.69 CES2 (0.33) CES2CES1FFAR3HDAC3HDAC1
SCHEMBL3768339 0.68 FAAH (0.41) CES2CES1TSHRFAAH
SCHEMBL14323585 0.68 FAAH (0.41) CES2CES1TSHRFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0038471-B1 BETA-GAMMA-UNSATURATED KETONES AND ISOPRENOIC DIENONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PERFUME COMPOUNDS AND FLAVOURINGS Consortium für elektrochemische Industrie GmbH (DE) 1984-11-14 EP disclosed
US-4385185-A β-γ-Unsaturated ketones and isoprenoid 2,6 diones, a process for producing the same and their use as fragrant and flavoring substances CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1983-05-24 US disclosed
EP-0038471-A1 Beta-gamma-unsaturated ketones and isoprenoic dienones, process for their preparation and their use as perfume compounds and flavourings Consortium für elektrochemische Industrie GmbH (DE) 1981-10-28 EP disclosed