Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11743781 | 0.82 | MAPK1 (0.37) | MAPTDGAT1ALDH1A1MMP1MMP9 | |
| SCHEMBL18691994 | 0.82 | CTSK (0.32) | MAPTDGAT1ALDH1A1LMNA | |
| SCHEMBL27163495 | 0.81 | DGAT1 (0.35) | MAPTPOLBDGAT1ALDH1A1LMNA | |
| SCHEMBL16837735 | 0.81 | ALDH1A1 (0.36) | MAPTDGAT1ALDH1A1LMNATSHR | |
| SCHEMBL27412775 | 0.80 | MAPT (0.41) | MAPTCYP2C19POLBTDP1DGAT1 | |
| Ammonia Solution, Strong SCHEMBL16982684 | 0.78 | MAPT (0.40) | MAPTCYP2C19POLBTDP1DGAT1 | |
| SCHEMBL631049 | 0.78 | CYP2C19 (0.38) | MAPTCYP2C19POLBTDP1DGAT1 | |
| SCHEMBL3181055 | 0.78 | CYP2C19 (0.38) | MAPTCYP2C19POLBTDP1DGAT1 | |
| SCHEMBL24118570 | 0.78 | DGAT1 (0.33) | MAPTDGAT1 | |
| SCHEMBL28709492 | 0.78 | LMNA (0.33) | MAPTTDP1DGAT1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064150-A | SELECTIVE GAMMA-ALKYLATION OF ALPHA,BETA-UNSATURATED ACIDS WITH ALLYLIC ELECTROPHILES, DICOPPER(I) DIENOLATES | UNIVERSITY OF ILLINOIS FOUNDATION (US) | 1977-12-20 | — | — | US | disclosed |