Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 4/20 | 0.43 |
| ▸ | NOS3 | P29474 | 3/20 | 0.43 |
| ▸ | NOS2 | P35228 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | OGT | O15294 | 1/20 | 0.40 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11043599 | 0.93 | KMO (0.50) | KMONOS1NOS3NOS2CYP1A2 | |
| SCHEMBL9370924 | 0.88 | KMO (0.49) | KMONOS1NOS3NOS2CYP1A2 | |
| SCHEMBL9680309 | 0.83 | KMO (0.59) | KMONOS1NOS3NOS2CYP1A2 | |
| SCHEMBL1115840 | 0.76 | KMO (0.72) | KMONOS1NOS3NOS2CYP1A2 | |
| SCHEMBL522196 | 0.76 | NOS1 (0.53) | KMONOS1NOS3NOS2CYP1A2 | |
| SCHEMBL7067142 | 0.76 | KMO (0.52) | KMONOS1NOS3NOS2CYP1A2 | |
| SCHEMBL11070843 | 0.75 | KMO (0.50) | KMONOS1NOS3NOS2CYP1A2 | |
| SCHEMBL30295627 | 0.74 | KMO (0.68) | KMONOS1NOS3NOS2CYP1A2 | |
| SCHEMBL9874657 | 0.73 | KMO (0.52) | KMONOS1NOS3NOS2CYP1A2 | |
| SCHEMBL11040016 | 0.73 | NOS1 (0.53) | KMONOS1NOS3NOS2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0045892-B1 | PROCESS FOR THE PREPARATION OF PRECURSORS FOR POLYMERS CONTAINING THE OXAZOLIN-2-ONE RING, AND THEIR USE IN THE PRODUCTION OF HIGH MOLECULAR WEIGHT POLYMERS | BAYER AG (DE) | 1984-02-01 | — | — | EP | disclosed |
| EP-0050780-B1 | ISOCYANATO-OXAZOLINONES, METHOD FOR THE PREPARATION OF OXAZOLIDIN-2-ONE RINGS CONTAINING PLASTICS PRECURSORS, AND THEIR USE IN THE PREPARATION OF HIGH-MOLECULAR PLASTICS | BAYER AG (DE) | 1983-12-28 | — | — | EP | disclosed |
| US-4350781-A | Process for the preparation of polymer precursors containing oxazolin-2-one rings | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-21 | — | — | US | disclosed |
| EP-0050780-A1 | Isocyanato-oxazolinones, method for the preparation of oxazolidin-2-one rings containing plastics precursors, and their use in the preparation of high-molecular plastics | BAYER AG (DE) | 1982-05-05 | — | — | EP | disclosed |
| EP-0045892-A1 | Process for the preparation of precursors for polymers containing the oxazolin-2-one ring, and their use in the production of high molecular weight polymers | BAYER AG (DE) | 1982-02-17 | — | — | EP | disclosed |