Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 6/20 | 0.33 |
| ▸ | RAB9A | P51151 | 6/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MITF | O75030 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 6/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10867445 | 0.82 | ALDH1A1 (0.42) | ALDH1A1HSD17B10CYP3A4TSHRKMT2A | |
| SCHEMBL6684382 | 0.76 | L3MBTL1 (0.45) | ALDH1A1TSHRKMT2AL3MBTL1NPC1 | |
| SCHEMBL11670370 | 0.74 | TDP1 (0.38) | ALDH1A1HSD17B10CYP3A4TSHRKMT2A | |
| SCHEMBL11776507 | 0.73 | GAA (0.38) | ALDH1A1HSD17B10CYP3A4TSHRKMT2A | |
| SCHEMBL11061618 | 0.73 | ALDH1A1 (0.57) | ALDH1A1HSD17B10CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL11005137 | 0.72 | AR (0.33) | ALDH1A1HSD17B10CYP3A4TSHRKMT2A | |
| SCHEMBL11252416 | 0.71 | ALDH1A1 (0.55) | ALDH1A1HSD17B10CYP3A4TSHRKMT2A | |
| SCHEMBL11180796 | 0.70 | CYP3A4 (0.46) | ALDH1A1HSD17B10CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL3104267 | 0.70 | ALDH1A1 (0.58) | ALDH1A1HSD17B10CYP3A4TSHRKMT2A | |
| SCHEMBL258349 | 0.69 | ACHE (0.41) | ALDH1A1CYP3A4TSHRKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0054149-B1 | TRIFLUOROMETHOXYPHENYL-(DI)THIOPHOSPHORIC-ACID ESTERS, PROCESS FOR PREPARING THEM AND THEIR USE AS PESTICIDES | BASF Aktiengesellschaft (DE) | 1984-05-16 | — | — | EP | disclosed |