SCHEMBL1104154

SCHEMBL1104154

CCC(C)(C)C(=O)NC(=O)NC1CCC(C(O)O)CC1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 6/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
EPHX2 P34913 7/20 0.36
KDM5A P29375 1/20 0.36
CCR2 P41597 1/20 0.36
ATM Q13315 1/20 0.36
RECQL P46063 1/20 0.35
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14008106 0.89 CCR2 (0.41) EPHX1L3MBTL1KDM5ACCR2ALDH1A1
SCHEMBL10110683 0.80 RECQL (0.39) EPHX1L3MBTL1EPHX2CCR2RECQL
SCHEMBL13921990 0.78 RECQL (0.36) EPHX1L3MBTL1EPHX2KDM5ACCR2
SCHEMBL18909746 0.76 CCR2 (0.49) EPHX1KDM5ACCR2ALDH1A1
SCHEMBL18909861 0.70 CCR2 (0.50) EPHX1CCR2RECQLKDM4EALDH1A1
SCHEMBL21207007 0.69 BTK (0.51) EPHX1L3MBTL1EPHX2
SCHEMBL15132215 0.69 PKM (0.40) EPHX2KDM5ACCR2
SCHEMBL14114344 0.68 PDK1 (0.56) EPHX1EPHX2CCR2RECQLKDM4E
SCHEMBL14114327 0.68 CCR2 (0.42) KDM5ACCR2RECQLALDH1A1
SCHEMBL14428590 0.68 RIPK1 (0.45) L3MBTL1CCR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-20100081771-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-7338748-B2 Polymerizable composition and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2008-03-04 US disclosed