Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11044416 | 0.88 | BRD4 (0.45) | BRD4GAACYP3A4MAPTALDH1A1 | |
| SCHEMBL11038859 | 0.84 | BRD4 (0.39) | BRD4GAACYP3A4MAPTALDH1A1 | |
| SCHEMBL11045652 | 0.82 | GAA (0.57) | BRD4GAAHTR1ACYP3A4MAPT | |
| SCHEMBL11041605 | 0.79 | BRD4 (0.39) | BRD4GAACYP3A4MAPTALDH1A1 | |
| SCHEMBL3821050 | 0.75 | PARP1 (0.37) | BRD4CYP3A4MAPTALDH1A1DRD5 | |
| SCHEMBL11044464 | 0.73 | GAA (0.68) | GAADRD5 | |
| SCHEMBL333847 | 0.69 | GAA (0.63) | BRD4GAACYP3A4MAPTALDH1A1 | |
| SCHEMBL11040239 | 0.69 | ATM (0.37) | GAACYP3A4MAPTALDH1A1 | |
| SCHEMBL11043204 | 0.68 | BRD4 (0.44) | BRD4CYP3A4MAPTALDH1A1DRD5 | |
| Hydrochloric Acid SCHEMBL11042874 | 0.67 | BRD4 (0.38) | BRD4CYP3A4MAPTALDH1A1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116444-A2 | Improvements in or relating to benzazepine derivatives | ELI LILLY AND COMPANY (US) | 1984-08-22 | — | — | EP | disclosed |