SCHEMBL1104175

SCHEMBL1104175

CCC(C)(C)C(=O)NC1CCC(C(=O)OC)CC1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.41
CCR2 P41597 1/20 0.40
FKBP1A P62942 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ALDH1A1 P00352 2/20 0.38
GAA P10253 1/20 0.38
SSTR4 P31391 8/20 0.37
SSTR1 P30872 3/20 0.37
TP53 P04637 1/20 0.36
HSD11B1 P28845 1/20 0.35
KDM5A P29375 1/20 0.35
PKM P14618 1/20 0.35
PDK1 Q15118 1/20 0.35
PDK2 Q15119 1/20 0.35
PDK3 Q15120 1/20 0.35
PDK4 Q16654 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1104177 0.88 HSD11B1 (0.44) CCR2FKBP1AALDH1A1GAASSTR4
SCHEMBL18909746 0.86 CCR2 (0.49) CCR2ALDH1A1SSTR4SSTR1HSD11B1
SCHEMBL14114327 0.83 CCR2 (0.42) CCR2ALDH1A1GAASSTR4SSTR1
SCHEMBL19215805 0.80 SMN1; SMN2 (0.44) POLBFKBP1ASMN1; SMN2ALDH1A1GAA
SCHEMBL18909861 0.79 CCR2 (0.50) CCR2SMN1; SMN2ALDH1A1PDK1PDK2
SCHEMBL14114344 0.78 PDK1 (0.56) CCR2SMN1; SMN2ALDH1A1PDK1PDK2
SCHEMBL26106230 0.78 POLB (0.46) POLBSMN1; SMN2ALDH1A1GAATP53
SCHEMBL26106226 0.78 POLB (0.46) POLBSMN1; SMN2ALDH1A1GAATP53
SCHEMBL18546212 0.77 KMT2A (0.41) CCR2SMN1; SMN2SSTR4SSTR1KDM5A
SCHEMBL18546663 0.76 KMT2A (0.42) CCR2ALDH1A1SSTR4SSTR1KDM5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-20100081771-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-7507525-B2 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2009-03-24 US disclosed
US-7279539-B2 Alkali-soluble polymer and polymerizable composition thereof FUJIFILM CORPORATION (JP) 2007-10-09 US disclosed