Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.41 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11041569 | 0.88 | HPGD (0.53) | ALDH1A1TDP1PSMB5HPGDSMN1; SMN2 | |
| SCHEMBL11046557 | 0.86 | PSMB5 (0.48) | NLRP3SIRT2PSMB5THRBHPGD | |
| SCHEMBL11038572 | 0.86 | LMNA (0.53) | ALDH1A1SIRT2PSMB5THRBHPGD | |
| SCHEMBL11037929 | 0.86 | SIRT2 (0.55) | ALDH1A1KDM4ESIRT2TDP1THRB | |
| SCHEMBL11039230 | 0.86 | SIRT2 (0.45) | SIRT2TDP1LMNAFFAR1 | |
| SCHEMBL9799045 | 0.86 | RAB9A (0.53) | SIRT2SMN1; SMN2FFAR1MEN1KMT2A | |
| SCHEMBL11041218 | 0.86 | NPC1 (0.50) | ALDH1A1NLRP3SIRT2TDP1HPGD | |
| SCHEMBL11037849 | 0.85 | MEN1 (0.44) | ALDH1A1SIRT2TDP1PSMB5THRB | |
| SCHEMBL11041771 | 0.85 | RAB9A (0.55) | ALDH1A1SIRT2TDP1MEN1MAPT | |
| SCHEMBL11042909 | 0.84 | MAPT (0.46) | ALDH1A1SIRT2TDP1THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4490165-A | Meta-(phenylalkoxy)phenyl-N-methoxy-N-methylurea compounds, methods for preparing same and herbicidal use thereof | AMERICAN CYANAMID COMPANY (US) | 1984-12-25 | — | — | US | disclosed |