Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | RGS12 | O14924 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31254084 | 0.86 | ALDH1A1 (0.45) | HPGDHSD17B10KDM4EGAATSHR | |
| SCHEMBL510145 | 0.86 | ALDH1A1 (0.45) | HPGDHSD17B10KDM4EGAATSHR | |
| SCHEMBL15165881 | 0.86 | ALDH1A1 (0.64) | HPGDHSD17B10KDM4EGAATSHR | |
| SCHEMBL20045097 | 0.84 | HPGD (0.50) | HPGDHSD17B10KDM4EGAATSHR | |
| SCHEMBL12125341 | 0.84 | HPGD (0.66) | HPGDHSD17B10KDM4EGAATSHR | |
| SCHEMBL1173033 | 0.83 | GAA (0.57) | HPGDHSD17B10KDM4EGAATSHR | |
| SCHEMBL27999728 | 0.82 | IAPP (0.41) | HPGDHSD17B10KDM4EGAATSHR | |
| SCHEMBL4683962 | 0.82 | CA2 (0.50) | HPGDKDM4ENFKB1LMNAPOLB | |
| SCHEMBL4683959 | 0.82 | DHFR (0.38) | HPGDHSD17B10KDM4EGAATSHR | |
| SCHEMBL3668067 | 0.80 | FFAR1 (0.52) | HSD17B10LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116444-A2 | Improvements in or relating to benzazepine derivatives | ELI LILLY AND COMPANY (US) | 1984-08-22 | — | — | EP | disclosed |