Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | PTPRB | P23467 | 1/20 | 0.45 |
| ▸ | CDC25A | P30304 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | PTEN | P60484 | 1/20 | 0.45 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3692519 | 0.87 | NPSR1 (0.50) | FFAR1KEAP1LMNAL3MBTL1HSD17B10 | |
| SCHEMBL27616828 | 0.86 | IAPP (0.56) | L3MBTL1CYP1A2 | |
| SCHEMBL13286146 | 0.85 | BACE1 (0.64) | FFAR1KEAP1LMNAL3MBTL1FFAR4 | |
| SCHEMBL14110345 | 0.85 | NPSR1 (0.53) | FFAR1KEAP1LMNAL3MBTL1NPSR1 | |
| SCHEMBL23495102 | 0.84 | FFAR1 (0.55) | FFAR1KEAP1HSD17B10NPSR1CYP1A2 | |
| SCHEMBL31307940 | 0.84 | FFAR1 (0.55) | FFAR1KEAP1HSD17B10NPSR1CYP1A2 | |
| SCHEMBL8272808 | 0.84 | FFAR1 (0.50) | FFAR1KEAP1LMNAL3MBTL1RXRA | |
| SCHEMBL24021201 | 0.81 | ALOX5 (0.51) | FFAR1ALDH1A1CYP1A2FFAR4 | |
| SCHEMBL8573039 | 0.81 | RXRA (0.51) | FFAR1KEAP1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL15355980 | 0.81 | FFAR1 (0.52) | FFAR1KEAP1HSD17B10CYP1A2FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7812038-B2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2010-10-12 | — | — | US | disclosed |
| US-20060276476-A1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | BIEDIGER RONALD J | 2006-12-07 | — | — | US | disclosed |
| US-6972296-B2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC. (US) | 2005-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276476-A1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | VCAM1, ICAM1, ITGA1 | FFAR1 74/4885KEAP1 2602/4885LMNA 1820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.