SCHEMBL11042019

SCHEMBL11042019

COc1ccc(P(=O)(O)O)cc1N

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.53
LMNA P02545 1/20 0.53
HTT P42858 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
TDP1 Q9NUW8 2/20 0.50
CYP3A4 P08684 1/20 0.50
FBP1 P09467 1/20 0.49
MEN1 O00255 1/20 0.48
MAPT P10636 1/20 0.48
THRB P10828 1/20 0.48
KMT2A Q03164 1/20 0.48
GAA P10253 1/20 0.47
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
MMP1 P03956 1/20 0.46
MMP2 P08253 1/20 0.46
MMP9 P14780 1/20 0.46
MMP8 P22894 1/20 0.46
MMP13 P45452 1/20 0.46
TUBB4A P04350 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29505096 1.00 ALDH1A1 (0.53) ALDH1A1LMNAHTTL3MBTL1TDP1
Hydrochloric Acid SCHEMBL17493635 0.98 ALDH1A1 (0.52) ALDH1A1LMNAHTTL3MBTL1TDP1
SCHEMBL11406909 0.87 CA1 (0.43) ALDH1A1LMNAHTTL3MBTL1TDP1
SCHEMBL1491622 0.83 ALDH1A1 (0.52) ALDH1A1LMNAHTTL3MBTL1TDP1
SCHEMBL4406229 0.82 TSHR (0.48) ALDH1A1L3MBTL1TDP1CYP3A4FBP1
SCHEMBL17224528 0.79 FBP1 (0.44) ALDH1A1LMNATDP1CYP3A4FBP1
SCHEMBL11040491 0.76 CYP1A2 (0.54) ALDH1A1LMNAHTTL3MBTL1CYP3A4
SCHEMBL6118417 0.76 GAA (0.46) ALDH1A1LMNAHTTL3MBTL1TDP1
SCHEMBL6118428 0.76 ALDH1A1 (0.41) ALDH1A1LMNAHTTL3MBTL1TDP1
SCHEMBL10781577 0.76 CA2 (0.42) ALDH1A1LMNATDP1CYP3A4FBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4230618-A CELLULOSE ICI UNITED STATES, INC. (US) 1980-10-28 US claimed
US-20210251511-A1 ANALYSIS OF GAS SAMPLES FOR DETERMINATION OF PHYSIOLOGICAL STATES AND DISEASE STATES UNIV NEW YORK (US) 2021-08-19 US disclosed
US-9550861-B2 Method for producing polyaniline having self-doping function and antistatic agent containing polyaniline produced thereby OSAKA UNIVERSITY (JP) 2017-01-24 US disclosed
US-20160046767-A1 METHOD FOR PRODUCING POLYANILINE HAVING SELF-DOPING FUNCTION AND ANTISTATIC AGENT CONTAINING POLYANILINE PRODUCED THEREBY DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2016-02-18 US disclosed
US-4472308-A Azo dyestuffs containing an amino or acylated amino naphthol monosulfonic acid radical and at least one reactive phosphoric or phosphonic acid group ICI UNITED STATES, INC. (US) 1984-09-18 US disclosed
US-4230618-A CELLULOSE ICI UNITED STATES, INC. (US) 1980-10-28 US disclosed
US-4225491-A REACTIVE DYES FOR COTTON ICI UNITED STATES, INC. (US) 1980-09-30 US disclosed
US-3947435-A Disazo acid compounds containing one sulphonic acid group and one phosphonic or methyl-phosphinic acid group PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-03-30 US disclosed