Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | MAOB | P27338 | 2/20 | 0.63 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.59 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | PLK1 | P53350 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845348 | 0.90 | NPSR1 (0.79) | KMT2ANPSR1PARP10LMNAMAPK1 | |
| SCHEMBL1547683 | 0.84 | NQO1 (0.74) | KMT2AMAOBPARP10L3MBTL1ALDH1A1 | |
| SCHEMBL11576081 | 0.83 | KMT2A (0.69) | KMT2ANPSR1MAOBPARP10LMNA | |
| SCHEMBL30776959 | 0.83 | KMT2A (0.69) | KMT2ANPSR1MAOBPARP10LMNA | |
| Carbamic Acid SCHEMBL11793902 | 0.83 | PARP10 (0.61) | KMT2AMAOBPARP10L3MBTL1ALDH1A1 | |
| SCHEMBL845256 | 0.83 | L3MBTL1 (0.77) | KMT2ANPSR1MAOBPARP10LMNA | |
| Ammonia Solution, Strong SCHEMBL322908 | 0.82 | NQO1 (0.70) | KMT2AMAOBPARP10L3MBTL1PLK1 | |
| SCHEMBL6655854 | 0.81 | TSHR (0.70) | KMT2ANPSR1PARP10LMNAMAPK1 | |
| SCHEMBL20496443 | 0.81 | NPSR1 (0.67) | KMT2ANPSR1PARP10LMNAMAPK1 | |
| SCHEMBL11578668 | 0.81 | KMT2A (0.67) | KMT2ANPSR1PARP10LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160244435-A1 | EXPANDED THERAPEUTIC POTENTIAL IN NITROHETEROARYL ANTIMICROBIALS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-08-25 | — | — | US | disclosed |
| WO-2014205414-A1 | EXPANDED THERAPEUTIC POTENTIAL IN NITROHETEROARYL ANTIMICROBIALS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-12-24 | — | — | WO | disclosed |
| US-4453009-A | HALOGEN-FLUORINE EXCHANGE BETWEEN CORRESPONDING 4-HALOGENO- OR 4,4-DIHALOGENOBENZOPHENONE AND ALKALI FLUORIDE | MITSUI TOATSU CHEMICALS, INC. (JP) | 1984-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160244435-A1 | EXPANDED THERAPEUTIC POTENTIAL IN NITROHETEROARYL ANTIMICROBIALS | NQO1, TXN2, MPO | KMT2A 4713/4885NPSR1 4048/4885MAOB 1961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.