Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.47 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.47 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.47 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22609241 | 0.88 | PLAAT3 (0.58) | LMNAFFAR1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL655425 | 0.84 | SMN1; SMN2 (0.67) | LMNAFFAR1HDAC3HDAC4HDAC1 | |
| SCHEMBL28313826 | 0.82 | LMNA (0.47) | LMNAFFAR1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL23003726 | 0.82 | LMNA (0.56) | LMNAFFAR1HDAC3HDAC4HDAC1 | |
| SCHEMBL710419 | 0.82 | HDAC1 (0.69) | LMNAFFAR1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL11039858 | 0.81 | HDAC3 (0.54) | FFAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL11037383 | 0.81 | PLAAT3 (0.60) | FFAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL658360 | 0.80 | LMNA (0.54) | LMNAFFAR1 | |
| SCHEMBL3940464 | 0.80 | LMNA (0.50) | LMNAFFAR1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL8813092 | 0.79 | SMN1; SMN2 (0.60) | LMNAFFAR1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038343-B1 | SUBSTITUTED CARBOXYLIC CETO-ACIDS, PROCESS FOR THE PREPARATION THEREOF, USE THEREOF AND MEDICINAL COMPOSITIONS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1984-12-27 | — | — | EP | disclosed |