Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 1/20 | 0.58 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.58 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.58 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.58 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.50 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | AOC2 | O75106 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11042340 | 0.88 | LMNA (0.55) | PLAAT3PLAAT5PLAAT2PLAAT4FFAR1 | |
| SCHEMBL193318 | 0.83 | FFAR1 (0.79) | PLAAT3PLAAT5PLAAT2PLAAT4FFAR1 | |
| SCHEMBL16595351 | 0.82 | NAAA (0.46) | PLAAT3PLAAT5PLAAT2PLAAT4FFAR1 | |
| Hydrochloric Acid SCHEMBL29184696 | 0.81 | FFAR1 (0.76) | PLAAT3PLAAT5PLAAT2PLAAT4FFAR1 | |
| Hydrochloric Acid SCHEMBL28568409 | 0.81 | FFAR1 (0.76) | PLAAT3PLAAT5PLAAT2PLAAT4FFAR1 | |
| SCHEMBL9747544 | 0.81 | ESR1 (0.54) | PLAAT3PLAAT5PLAAT2PLAAT4FFAR1 | |
| SCHEMBL7332325 | 0.80 | FFAR1 (0.58) | PLAAT3PLAAT5PLAAT2PLAAT4FFAR1 | |
| SCHEMBL258545 | 0.80 | KEAP1 (0.67) | PLAAT3PLAAT5PLAAT2PLAAT4FFAR1 | |
| SCHEMBL4824446 | 0.80 | FFAR1 (0.54) | PLAAT3PLAAT5PLAAT2PLAAT4FFAR1 | |
| SCHEMBL7271458 | 0.79 | PLAAT3 (0.59) | PLAAT3PLAAT5PLAAT2PLAAT4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3731840-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | Orfan Biotech Inc. (US) | 2020-11-04 | — | — | EP | disclosed |