Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11040212 | 0.99 | CYP1A2 (0.39) | LMNAALDH1A1MEN1KMT2APOLB | |
| SCHEMBL11045088 | 0.90 | GAA (0.47) | ALDH1A1MEN1KMT2AGAAHPGD | |
| Hydrochloric Acid SCHEMBL11039759 | 0.84 | ACHE (0.41) | LMNAALDH1A1MEN1KMT2APOLB | |
| SCHEMBL11044939 | 0.83 | ADRA2A (0.37) | ALDH1A1MEN1KMT2ACYP2D6ADRA2A | |
| Hydrochloric Acid SCHEMBL11043462 | 0.82 | KMT2A (0.41) | LMNAALDH1A1MEN1KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL11040444 | 0.82 | MEN1 (0.38) | ALDH1A1MEN1KMT2AGAACYP2D6 | |
| Hydrochloric Acid SCHEMBL11040321 | 0.79 | LMNA (0.40) | LMNAMEN1KMT2APOLBGAA | |
| Hydrochloric Acid SCHEMBL11042474 | 0.77 | CASP1 (0.36) | ALDH1A1MEN1KMT2AHPGDTSHR | |
| Hydrochloric Acid SCHEMBL11040671 | 0.76 | SCN4A (0.33) | LMNAALDH1A1MEN1KMT2AGAA | |
| SCHEMBL10854087 | 0.76 | MEN1 (0.49) | LMNAALDH1A1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448971-A | Hypoglycemic 5-phenyl-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1984-05-15 | — | — | US | disclosed |
| US-4407811-A | Hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1983-10-04 | — | — | US | disclosed |
| US-4399296-A | TRIMETHYLSILYL CYANOHYDRIN INTERMEDIATES | PFIZER INC. (US) | 1983-08-16 | — | — | US | disclosed |
| US-4367234-A | HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1983-01-04 | — | — | US | disclosed |