Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 8/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.66 |
| ▸ | PGR | P06401 | 6/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.66 |
| ▸ | TNF | P01375 | 1/20 | 0.66 |
| ▸ | IL6 | P05231 | 1/20 | 0.66 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.66 |
| ▸ | AR | P10275 | 1/20 | 0.66 |
| ▸ | GLUL | P15104 | 1/20 | 0.66 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.66 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11042626 | 1.00 | NR3C2 (0.66) | NR3C2NR3C1PGRHIF1AHSD17B10 | |
| SCHEMBL10945378 | 0.92 | NR3C2 (0.68) | NR3C2NR3C1PGRHIF1AHSD17B10 | |
| SCHEMBL6857093 | 0.92 | NR3C2 (0.72) | NR3C2NR3C1PGRHIF1AHSD17B10 | |
| SCHEMBL11016342 | 0.92 | NR3C2 (0.72) | NR3C2NR3C1PGRHIF1AHSD17B10 | |
| SCHEMBL6857090 | 0.92 | NR3C2 (0.72) | NR3C2NR3C1PGRHIF1AHSD17B10 | |
| SCHEMBL10945334 | 0.92 | NR3C2 (0.68) | NR3C2NR3C1PGRHIF1AHSD17B10 | |
| Prednival SCHEMBL11585728 | 0.91 | HIF1A (0.73) | NR3C2NR3C1PGRHIF1AHSD17B10 | |
| Prednival SCHEMBL25387 | 0.91 | HIF1A (0.73) | NR3C2NR3C1PGRHIF1AHSD17B10 | |
| Succinic Acid SCHEMBL22042712 | 0.91 | NR3C1 (0.67) | NR3C2NR3C1PGRHIF1AHSD17B10 | |
| SCHEMBL1945621 | 0.91 | NR3C1 (0.67) | NR3C2NR3C1PGRHIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435390-A | Hydrocortisone derivatives, the preparation and use thereof | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-03-06 | — | — | US | disclosed |