Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.59 |
| ▸ | PGR | P06401 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11044522 | 0.88 | NR3C1 (0.54) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| Hydrochloric Acid SCHEMBL7351252 | 0.87 | ALDH1A1 (0.72) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| Hydrochloric Acid SCHEMBL11041942 | 0.86 | NR3C1 (0.52) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL11044555 | 0.85 | KCNH2 (0.60) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL11046347 | 0.85 | NR3C1 (0.62) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| Iodide SCHEMBL11041065 | 0.84 | NR3C1 (0.61) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL11202004 | 0.84 | PDE3B (0.61) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL11045054 | 0.82 | CRBN (0.62) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL11042441 | 0.82 | NR3C1 (0.66) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL11042336 | 0.81 | NR3C1 (0.84) | NR3C1PGRSLC6A4KCNH2PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487772-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4468402-A | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454130-A | CARDIOTONIC, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |