SCHEMBL1104282

SCHEMBL1104282

O=C(O)CCCCCSCC(O)CO

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
BHMT Q93088 2/20 0.49
TSHR P16473 3/20 0.44
LMNA P02545 2/20 0.44
NFKB1 P19838 1/20 0.44
PMP22 Q01453 1/20 0.44
GPR84 Q9NQS5 3/20 0.43
FFAR1 O14842 2/20 0.43
FFAR4 Q5NUL3 2/20 0.43
PLA2G4B P0C869 1/20 0.39
PPARG P37231 2/20 0.38
PPARD Q03181 2/20 0.38
PPARA Q07869 2/20 0.38
ALDH1A1 P00352 1/20 0.38
SLC22A6 Q4U2R8 1/20 0.38
SLC22A8 Q8TCC7 1/20 0.38
TLR2 O60603 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1104269 0.98 BHMT (0.47) BHMTTSHRLMNANFKB1PMP22
SCHEMBL9233298 0.92 TSHR (0.50) BHMTTSHRLMNANFKB1PMP22
Stearic Acid SCHEMBL28585846 0.92 FFAR4 (0.56) TSHRGPR84FFAR1FFAR4PLA2G4B
SCHEMBL1104232 0.84 LMNA (0.54) BHMTTSHRLMNAPLA2G4BALDH1A1
SCHEMBL6302289 0.84 LMNA (0.40) LMNAALDH1A1
SCHEMBL21676202 0.84 LMNA (0.40) LMNAALDH1A1
SCHEMBL6310446 0.82 LMNA (0.42) LMNAALDH1A1
SCHEMBL15430561 0.81 PLA2G4B (0.46) BHMTTSHRLMNANFKB1PMP22
Azelaic Acid SCHEMBL31615119 0.80 TSHR (0.63) TSHRLMNANFKB1PMP22GPR84
Azelaic Acid SCHEMBL1495263 0.80 TSHR (0.63) TSHRLMNANFKB1PMP22GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-20100081771-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-20100081771-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
EP-2168767-A1 Method of preparing lithographic printing plate Fujifilm Corporation (JP) 2010-03-31 EP disclosed