SCHEMBL1104286

SCHEMBL1104286

CC(CO)(CO)NC(=O)CCC(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PHF8 Q9UPP1 6/20 0.45
KDM2A Q9Y2K7 6/20 0.45
KDM4E B2RXH2 4/20 0.45
KDM5C P41229 4/20 0.45
EGLN1 Q9GZT9 4/20 0.45
KDM6B O15054 2/20 0.44
FOLH1 Q04609 1/20 0.44
KDM7A Q6ZMT4 1/20 0.43
NAALAD2 Q9Y3Q0 1/20 0.39
LMNA P02545 3/20 0.39
ALKBH5 Q6P6C2 1/20 0.39
SUCNR1 Q9BXA5 1/20 0.39
SLC15A2 Q16348 1/20 0.37
ALDH1A1 P00352 2/20 0.35
RXFP1 Q9HBX9 1/20 0.34
CYP1A1 P04798 1/20 0.33
KMT2A Q03164 1/20 0.33
FFAR3 O14843 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12328992 0.88 ALDH1A1 (0.46) LMNAALDH1A1KMT2A
SCHEMBL12328408 0.88 SLC22A6 (0.44) NAALAD2LMNAALDH1A1POLB
SCHEMBL12328518 0.86 TSHR (0.46) LMNAALDH1A1KMT2A
SCHEMBL12328517 0.81 PHF8 (0.47) PHF8KDM2AKDM4EKDM5CEGLN1
SCHEMBL10179 0.80 HDAC3 (0.46) ALDH1A1KMT2AFFAR3HDAC3HDAC1
SCHEMBL12386591 0.79 PHF8 (0.50) PHF8KDM2AKDM4EKDM5CEGLN1
SCHEMBL2859890 0.79 PHF8 (0.50) PHF8KDM2AKDM4EKDM5CEGLN1
SCHEMBL10269896 0.79 TSHR (0.52) KDM4ELMNAALDH1A1KMT2APOLB
SCHEMBL11522117 0.78 ALDH1A1 (0.44) KDM4EALDH1A1KMT2AHDAC3HDAC1
SCHEMBL13317954 0.78 ALDH1A1 (0.36) NAALAD2ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
EP-2042532-B1 Polymerizable composition and planographic printing plate precursor using the same, alkalisoluble polyurethane resin, and process for producing diol compound FUJIFILM CORP (JP) 2011-09-14 EP disclosed
US-7741011-B2 Polymerizable composition and planographic printing plate precursor using the same, alkali-soluble polyurethane resin, and process for producing diol compound FUJIFILM CORPORATION (JP) 2010-06-22 US disclosed
US-20100081771-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-20100081771-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-20090087785-A1 POLYMERIZABLE COMPOSITION AND PLANOGRAPHIC PRINTING PLATE PRECURSOR USING THE SAME, ALKALI-SOLUBLE POLYURETHANE RESIN, AND PROCESS FOR PRODUCING DIOL COMPOUND FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
EP-2042532-A2 Polymerizable composition and planographic printing plate precursor using the same, alkalisoluble polyrethane resin, an process for producing diol compound FUJIFILM Corporation (JP) 2009-04-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090087785-A1 POLYMERIZABLE COMPOSITION AND PLANOGRAPHIC PRINTING PLATE PRECURSOR USING THE SAME, ALKALI-SOLUBLE POLYURETHANE RESIN, AND PROCESS FOR PRODUCING DIOL COMPOUND PAH, RPN1, RER1 PHF8 369/4885KDM2A 699/4885KDM4E 1931/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.