Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 13/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9324636 | 0.87 | ALDH1A1 (0.54) | ALKBH5ALDH1A1MAPTGAAHTT | |
| SCHEMBL10405696 | 0.87 | ALDH1A1 (0.54) | ALKBH5ALDH1A1MAPTGAAHTT | |
| SCHEMBL8990127 | 0.85 | ALKBH5 (0.54) | ALKBH5TSHRKMT2AMEN1 | |
| SCHEMBL11807463 | 0.85 | ALKBH5 (0.51) | ALKBH5ALDH1A1MAPTGAAHTT | |
| SCHEMBL67421 | 0.84 | ALKBH5 (0.66) | ALKBH5ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL11437033 | 0.83 | ALKBH5 (0.49) | ALKBH5ALDH1A1MAPTGAAHTT | |
| SCHEMBL11647578 | 0.82 | ALKBH5 (0.52) | ALKBH5TSHRALDH1A1MAPTGAA | |
| SCHEMBL1819463 | 0.81 | ALKBH5 (0.61) | ALKBH5TSHRALDH1A1MAPTGAA | |
| SCHEMBL10654204 | 0.80 | ALDH1A1 (0.60) | ALKBH5ALDH1A1MAPTGAAHTT | |
| SCHEMBL10873349 | 0.78 | ALKBH5 (0.42) | ALKBH5TSHRALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4490151-A | Disazo sulfophenylpyrazolonestilbene dyes and direct dyes to color cellulose black | CROMPTON AND KNOWLES CORPORATION (US) | 1984-12-25 | — | — | US | disclosed |
| US-4455258-A | Disazo sulfophenylpyrazolone-sulfostilbene dyes | CROMPTON AND KNOWLES CORPORATION (US) | 1984-06-19 | — | — | US | disclosed |
| US-4218432-A | Coloring agent and a composition including the same for coloring toilet bowl flushing water | YAMAMOTO KAGAKU GOSEI CO., LTD. (JP) | 1980-08-19 | — | — | US | disclosed |
| US-4144231-A | Soluble trisazo dyestuffs containing a 2-phenyl-benzimidazolyl, -benzoxazolyl or -benzthiazolyl middle component | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-03-13 | — | — | US | disclosed |
| US-4143033-A | WATER-SOLUBLE DISAZO DYESTUFFS CONTAINING A 2-PHENYL-BENZIMIDAZOLYL,-BENZOXAZOLYL OR-BENZTHIAZOLYL MIDDLE COMPONENT | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-03-06 | — | — | US | disclosed |