SCHEMBL1104411

SCHEMBL1104411

FC(F)(F)c1cccc(-c2nnc(S)n2-c2ccccc2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.49
HSD17B10 Q99714 1/20 0.49
NPSR1 Q6W5P4 3/20 0.45
ALDH1A1 P00352 2/20 0.44
LMNA P02545 1/20 0.44
POLB P06746 2/20 0.43
KMT2A Q03164 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
NPC1 O15118 1/20 0.43
HPGD P15428 1/20 0.43
RAB9A P51151 1/20 0.43
ADORA2A P29274 1/20 0.43
ADORA1 P30542 1/20 0.43
MAPT P10636 1/20 0.41
TSHR P16473 1/20 0.41
TP53 P04637 1/20 0.41
NOTUM Q6P988 2/20 0.41
LRRK2 Q5S007 2/20 0.41
AVPR1A P37288 1/20 0.41
SCN2A Q99250 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12110562 0.92 NPSR1 (0.50) KDM4EHSD17B10NPSR1ALDH1A1POLB
SCHEMBL13863179 0.88 KDM4E (0.46) KDM4EHSD17B10ALDH1A1POLBKMT2A
SCHEMBL13844458 0.84 AVPR1A (0.60) KDM4EHSD17B10NPSR1ALDH1A1LMNA
SCHEMBL1104408 0.84 KIF11 (0.46) KDM4EHSD17B10ALDH1A1LMNAKMT2A
SCHEMBL1104354 0.84 AVPR1A (0.47) KDM4EHSD17B10ALDH1A1KMT2ASMN1; SMN2
SCHEMBL1104431 0.83 ALDH1A1 (0.47) NPSR1ALDH1A1LMNAPOLBKMT2A
SCHEMBL14132456 0.81 RXFP1 (0.55) KDM4EHSD17B10ALDH1A1LMNASMN1; SMN2
SCHEMBL10012459 0.81 MAPK1 (0.54) KDM4EHSD17B10NPSR1ALDH1A1KMT2A
SCHEMBL1104395 0.80 AVPR1A (0.59) KDM4EHSD17B10ALDH1A1LMNAKMT2A
SCHEMBL12394769 0.78 ALDH1A1 (0.41) KDM4EHSD17B10NPSR1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120295204-A1 PROCESSING METHOD OF LITHOGRAPHIC PRINTING PLATE PREURSOR FUJIFILM CORPORATION (JP) 2012-11-22 US disclosed
US-20120295204-A1 PROCESSING METHOD OF LITHOGRAPHIC PRINTING PLATE PREURSOR FUJIFILM CORPORATION (JP) 2012-11-22 US disclosed
US-8257913-B2 Processing method of lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-09-04 US disclosed
US-8257913-B2 Processing method of lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-09-04 US disclosed
US-8168370-B2 Photosensitive composition which included photopolymerization initiator; graft polymer binder FUJIFILM CORPORATION (JP) 2012-05-01 US disclosed
US-8168370-B2 Photosensitive composition which included photopolymerization initiator; graft polymer binder FUJIFILM CORPORATION (JP) 2012-05-01 US disclosed
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-7985535-B2 Image-forming method and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-07-26 US disclosed
US-7985535-B2 Image-forming method and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-07-26 US disclosed
US-20070212641-A1 Lithographic printing plate precursor and method for preparation of lithographic printing plate FUJIFILM CORPORATION (JP) 2007-09-13 US disclosed
US-20070207411-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-09-06 US disclosed
US-20070207411-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-09-06 US disclosed
EP-1640805-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2007-08-22 EP disclosed
US-20070184387-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-08-09 US disclosed
US-20070184387-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-08-09 US disclosed
US-20070128550-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-06-07 US disclosed
US-20070128550-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-06-07 US disclosed
US-20070020563-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. 2007-01-25 US disclosed
US-20070020563-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. 2007-01-25 US disclosed