SCHEMBL1104431

SCHEMBL1104431

FC(F)(F)c1cc(-n2c(S)nnc2-c2ccccc2)cc(C(F)(F)F)c1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
GAA P10253 1/20 0.47
NPSR1 Q6W5P4 1/20 0.41
POLB P06746 1/20 0.40
KMT2A Q03164 1/20 0.40
AVPR1A P37288 1/20 0.40
HPGD P15428 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HSD11B1 P28845 1/20 0.38
LMNA P02545 1/20 0.38
MAPK1 P28482 1/20 0.38
LRRK2 Q5S007 4/20 0.38
GSR P00390 2/20 0.38
KIF11 P52732 1/20 0.37
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
KDR P35968 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12394769 0.92 ALDH1A1 (0.41) ALDH1A1GAANPSR1POLBKMT2A
SCHEMBL12110562 0.89 NPSR1 (0.50) ALDH1A1NPSR1POLBKMT2AHPGD
SCHEMBL1104408 0.87 KIF11 (0.46) ALDH1A1GAAKMT2AAVPR1AHPGD
SCHEMBL1104354 0.84 AVPR1A (0.47) ALDH1A1GAAKMT2AAVPR1AHPGD
SCHEMBL1104411 0.83 KDM4E (0.49) ALDH1A1NPSR1POLBKMT2AAVPR1A
SCHEMBL13197412 0.80 AVPR1A (0.50) ALDH1A1GAANPSR1POLBKMT2A
SCHEMBL1104395 0.79 AVPR1A (0.59) ALDH1A1KMT2AAVPR1AHPGDSMN1; SMN2
SCHEMBL13197418 0.76 AVPR1A (0.45) ALDH1A1GAANPSR1KMT2AAVPR1A
SCHEMBL11511067 0.76 AVPR1A (0.59) ALDH1A1KMT2AAVPR1AHPGDSMN1; SMN2
SCHEMBL1104398 0.75 AVPR1A (0.47) ALDH1A1KMT2AAVPR1AHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120295204-A1 PROCESSING METHOD OF LITHOGRAPHIC PRINTING PLATE PREURSOR FUJIFILM CORPORATION (JP) 2012-11-22 US disclosed
US-8257913-B2 Processing method of lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-09-04 US disclosed
US-8257913-B2 Processing method of lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-09-04 US disclosed
US-8168370-B2 Photosensitive composition which included photopolymerization initiator; graft polymer binder FUJIFILM CORPORATION (JP) 2012-05-01 US disclosed
US-8168370-B2 Photosensitive composition which included photopolymerization initiator; graft polymer binder FUJIFILM CORPORATION (JP) 2012-05-01 US disclosed
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-7985535-B2 Image-forming method and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-07-26 US disclosed
US-7985535-B2 Image-forming method and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-07-26 US disclosed
US-20110168044-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2011-07-14 US disclosed
US-20070212641-A1 Lithographic printing plate precursor and method for preparation of lithographic printing plate FUJIFILM CORPORATION (JP) 2007-09-13 US disclosed
US-20070212641-A1 Lithographic printing plate precursor and method for preparation of lithographic printing plate FUJIFILM CORPORATION (JP) 2007-09-13 US disclosed
US-20070207411-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-09-06 US disclosed
US-20070207411-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-09-06 US disclosed
US-20070184387-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-08-09 US disclosed
US-20070184387-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-08-09 US disclosed
US-20070128550-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-06-07 US disclosed
US-20070128550-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-06-07 US disclosed
US-20070020563-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. 2007-01-25 US disclosed
US-20070020563-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. 2007-01-25 US disclosed