SCHEMBL1104354

SCHEMBL1104354

FC(F)(F)c1ccc(-c2nnc(S)n2-c2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AVPR1A P37288 1/20 0.47
KIF11 P52732 1/20 0.46
AKT1 P31749 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
RXFP1 Q9HBX9 1/20 0.42
KDM4E B2RXH2 5/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
HPGD P15428 1/20 0.41
GAA P10253 2/20 0.41
MGAM O43451 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
HSD17B10 Q99714 3/20 0.40
LRRK2 Q5S007 1/20 0.40
ALDH1A1 P00352 4/20 0.40
TSHR P16473 2/20 0.40
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
RXRG P48443 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1104408 0.94 KIF11 (0.46) AVPR1AKIF11AKT1KMT2AKDM4E
SCHEMBL13197419 0.89 AVPR1A (0.54) AVPR1AKIF11AKT1MEN1KMT2A
SCHEMBL11511067 0.87 AVPR1A (0.59) AVPR1AMEN1KMT2ARXFP1KDM4E
SCHEMBL10480447 0.85 RXRA (0.54) AVPR1AAKT1MEN1KMT2ARXFP1
SCHEMBL1104411 0.84 KDM4E (0.49) AVPR1AKMT2AKDM4ESMN1; SMN2HPGD
SCHEMBL12110562 0.84 NPSR1 (0.50) KMT2AKDM4ESMN1; SMN2HPGDHSD17B10
SCHEMBL1104431 0.84 ALDH1A1 (0.47) AVPR1AKIF11KMT2ASMN1; SMN2HPGD
SCHEMBL1104395 0.84 AVPR1A (0.59) AVPR1AMEN1KMT2ARXFP1KDM4E
SCHEMBL1104407 0.83 AVPR1A (0.51) AVPR1AMEN1KMT2ARXFP1KDM4E
SCHEMBL1104404 0.81 AVPR1A (0.57) AVPR1AMEN1KMT2ARXFP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120295204-A1 PROCESSING METHOD OF LITHOGRAPHIC PRINTING PLATE PREURSOR FUJIFILM CORPORATION (JP) 2012-11-22 US disclosed
US-20120295204-A1 PROCESSING METHOD OF LITHOGRAPHIC PRINTING PLATE PREURSOR FUJIFILM CORPORATION (JP) 2012-11-22 US disclosed
US-8257913-B2 Processing method of lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-09-04 US disclosed
US-8257913-B2 Processing method of lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-09-04 US disclosed
US-8168370-B2 Photosensitive composition which included photopolymerization initiator; graft polymer binder FUJIFILM CORPORATION (JP) 2012-05-01 US disclosed
US-8168370-B2 Photosensitive composition which included photopolymerization initiator; graft polymer binder FUJIFILM CORPORATION (JP) 2012-05-01 US disclosed
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-7985535-B2 Image-forming method and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-07-26 US disclosed
US-7985535-B2 Image-forming method and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-07-26 US disclosed
US-20070212641-A1 Lithographic printing plate precursor and method for preparation of lithographic printing plate FUJIFILM CORPORATION (JP) 2007-09-13 US disclosed
US-20070212641-A1 Lithographic printing plate precursor and method for preparation of lithographic printing plate FUJIFILM CORPORATION (JP) 2007-09-13 US disclosed
US-20070207411-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-09-06 US disclosed
US-20070207411-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-09-06 US disclosed
US-20070184387-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-08-09 US disclosed
US-20070184387-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-08-09 US disclosed
US-20070128550-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-06-07 US disclosed
US-20070128550-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-06-07 US disclosed
US-20070020563-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. 2007-01-25 US disclosed
US-20070020563-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. 2007-01-25 US disclosed