Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10641016 | 0.99 | PRMT6 (0.52) | PRMT6ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL8068562 | 0.84 | SIGMAR1 (0.51) | ADRB2ADRB1ADRB3ALDH1A1KDM4C | |
| SCHEMBL11043026 | 0.82 | OPRM1 (0.49) | ADRB2ADRB1ADRB3ALDH1A1KDM4C | |
| SCHEMBL10641868 | 0.81 | MAPK1 (0.42) | PRMT6ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL10638313 | 0.81 | ALDH1A1 (0.45) | ADRB2ADRB1ADRB3ALDH1A1KDM4C | |
| Hydrochloric Acid SCHEMBL10641997 | 0.81 | OPRM1 (0.48) | ADRB2ADRB1ADRB3ALDH1A1KDM4C | |
| SCHEMBL10642508 | 0.81 | CXCR4 (0.44) | ADRB2ADRB1ADRB3KDM4COPRK1 | |
| SCHEMBL10639738 | 0.81 | ALDH1A1 (0.41) | ADRB2ADRB1ADRB3ALDH1A1KDM4C | |
| SCHEMBL11042035 | 0.81 | ALDH1A1 (0.44) | ADRB2ADRB1ADRB3ALDH1A1KDM4C | |
| Hydrochloric Acid SCHEMBL10643081 | 0.80 | MAPK1 (0.41) | PRMT6ADRB2ADRB1ADRB3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448784-A | 1-(Aminoalkylphenyl and aminoalkylbenzyl)-indoles and indolines and analgesic method of use thereof | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1984-05-15 | — | — | US | claimed |