Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | RRM1 | P23921 | 1/20 | 0.32 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11156238 | 0.90 | KDM4E (0.49) | KDM4ENPC1ALDH1A1CA12CA1 | |
| SCHEMBL11042703 | 0.88 | KDM4E (0.41) | KDM4ENPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL11155674 | 0.82 | CA2 (0.39) | KDM4ENPC1ALDH1A1CA12CA1 | |
| SCHEMBL11155712 | 0.81 | KCNJ6 (0.36) | KDM4ENPC1ALDH1A1CA12CA1 | |
| SCHEMBL11047117 | 0.80 | ALDH1A1 (0.35) | KDM4ENPC1ALDH1A1CA12CA1 | |
| SCHEMBL11155912 | 0.80 | NPC1 (0.41) | KDM4ENPC1ALDH1A1CA1CA9 | |
| SCHEMBL10846988 | 0.80 | ALDH1A1 (0.35) | KDM4ENPC1ALDH1A1CA12CA1 | |
| SCHEMBL11157178 | 0.80 | ALDH1A1 (0.38) | KDM4ENPC1ALDH1A1CA12CA1 | |
| SCHEMBL11043929 | 0.79 | KDM4E (0.48) | KDM4ENPC1ALDH1A1CA12CA1 | |
| SCHEMBL11160117 | 0.79 | THRB (0.41) | ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030141-A2 | Herbicidal ureas and isoureas, preparation, compositions and use thereof, intermediates therefor and preparation of said intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-10 | — | — | EP | claimed |
| US-4460404-A | HERBICIDES PLANT GROWTH REGULATORS | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| EP-0030141-B1 | HERBICIDAL UREAS AND ISOUREAS, PREPARATION, COMPOSITIONS AND USE THEREOF, INTERMEDIATES THEREFOR AND PREPARATION OF SAID INTERMEDIATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-20 | — | — | EP | disclosed |
| US-4452627-A | HERBICIDE, PLANT GROWTH REGULATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-05 | — | — | US | disclosed |
| US-4370479-A | PLANT GROWTH REGULATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-01-25 | — | — | US | disclosed |
| EP-0030141-A2 | Herbicidal ureas and isoureas, preparation, compositions and use thereof, intermediates therefor and preparation of said intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-10 | — | — | EP | disclosed |