Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 2/20 | 0.37 |
| ▸ | EDNRB | P24530 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11156238 | 0.89 | KDM4E (0.49) | ALDH1A1KDM4ENPC1EDNRAEDNRB | |
| SCHEMBL11044243 | 0.80 | KDM4E (0.40) | ALDH1A1KDM4ENPC1EDNRAEDNRB | |
| SCHEMBL11283964 | 0.78 | LMNA (0.33) | ALDH1A1KDM4EEDNRAEDNRBGAA | |
| SCHEMBL11283976 | 0.78 | LMNA (0.33) | ALDH1A1KDM4EEDNRAEDNRBGAA | |
| SCHEMBL11155674 | 0.76 | CA2 (0.39) | ALDH1A1KDM4ENPC1CA12CA1 | |
| SCHEMBL11155712 | 0.75 | KCNJ6 (0.36) | ALDH1A1KDM4ENPC1CA12CA1 | |
| SCHEMBL11155912 | 0.74 | NPC1 (0.41) | ALDH1A1KDM4ENPC1GAACA1 | |
| SCHEMBL11160117 | 0.74 | THRB (0.41) | ALDH1A1CA1L3MBTL1CA2 | |
| SCHEMBL11286338 | 0.74 | CDK1 (0.42) | ALDH1A1KDM4ENPC1CA12CA1 | |
| SCHEMBL11047117 | 0.73 | ALDH1A1 (0.35) | ALDH1A1KDM4ENPC1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0015683-B1 | HERBICIDAL SULFONAMIDES, AND PREPARATION AND USE THEREOF | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-11-16 | — | — | EP | disclosed |
| US-4339267-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-07-13 | — | — | US | disclosed |